Skip to content
Free delivery on all orders over R750
Click Here
Chat with qualified skin therapists
Click Here
Free samples with every order
Click Here
Explore free gifts & promotions
Click Here
Hello 👋
Shop by Product Type

Shop All

Ampoules
Baby
Barrier Creams
BB & CC Creams
Body
Cleansers
Day Creams
Essences
Exfoliators
Eye Care
Foot Treatments
Foundation
Gift Vouchers
Haircare
Hand & Nail
Masks
Men
Micellar Waters
Moisturisers
Neck Creams
Night Creams
Oils
Oral Care
Serums
Starter Kits
Sunscreens
Supplements
Targeted Treatments
Toners
Tools & Devices
Shop by Brand

Shop All

Melumé Skinscience
SkinCeuticals
Huxley
NeoStrata®
Heliocare
Beaut™
Jorgobé
MartiDerm
Lamelle
iS Clinical
Hyaestic
PCA Skin
pHformula
ZO Skin Health
Kiehl's
mesoestetic
Obagi
La Roche-Posay
CeraVe
Exuviance
FEEV
Shop by Concern
Actinic Keratosis
Adult Acne
Atopic Eczema
Blackheads
Expression Lines
Eyelash & Eyebrow
Keratosis Pilaris
Lips
Perioral Dermatitis
Post-Acne Marks
Post-Treatment
Pregnancy
Psoriasis
Redness
Scars
Seborrhoeic Dermatitis
Stretch Marks
Shop by Science

Shop All

Retinoids
Vitamin C
Hyaluronic Acid
Azelaic Acid
Glycolic Acid
Arbutin
Peptides
Gluconolactone
Extremozymes
Growth Factors
Ceramides
Centella Asiatica
Iron Oxide
Niacinamide
Kojic Acid
Co-enzyme Q10
Shop by Skin Type
Dark Marks
Dry & Sensitive
Early Ageing, Fine Lines
Mature, Sun Damaged
Normal or Combination
Oily, Acne-Prone
Red, Rosacea-Prone
Shop by Age
Teen
60+
50s
40s
30s
20s
My Account
  • Become a Member
  • Promotions
  • Skin Assessment
  • Video Consultations
  • Learn
  • Dr Ian Webster
  • Contact Us

Introducing Video Consultations

Hyper-personalised one-on-one product advice with a qualified skin therapist.
Book a Session
  • Sign-In
R0.00 0 Cart
Brands

Featured Brands

  • Biretix
  • Thymuskin
  • Melumé Skinscience
  • SkinCeuticals
  • Huxley
  • NeoStrata®
  • Heliocare
  • Beaut™
  • Jorgobé
  • MartiDerm
  • Lamelle
  • Dermanique
  • iS Clinical
  • Hyaestic
  • PCA Skin
  • pHformula
  • ZO Skin Health
  • Kiehl's
  • mesoestetic
  • Obagi
  • Geske
  • La Roche-Posay
  • CeraVe
  • Colorescience
  • Exuviance
  • Endocare
  • Aveeno
  • Avène
  • Bioderma
  • ISDIN

Shop All

A regenerating anti-ageing serum that reveals a smooth glow!

MARTIDERM NIGHT RENEW SERUM
Skin Type

Skin Type

  • Mature, Sun Damaged
  • Normal or Combination
  • Dark Marks
  • Early Ageing, Fine Lines
  • Dry & Sensitive
  • Oily, Acne-Prone
  • Red, Rosacea-Prone

Shop All

  • Age
Teen
60+
50s
40s
30s
20s

Skin Concern

  • Stretch Marks
  • Eyelash & Eyebrow
  • Actinic Keratosis
  • Adult Acne
  • Post-Acne Marks
  • Expression Lines
  • Perioral Dermatitis
  • Keratosis Pilaris
  • Seborrhoeic Dermatitis
  • Lips
  • Blackheads
  • Atopic Eczema
  • Post-Treatment
  • Pregnancy
  • Psoriasis
  • Redness
  • Scars

Shop All

Huxley’s Conditioning Collection

SHOP NOW
Product Type

Product Type

  • Baby
  • Barrier Creams
  • Cleansers
  • Sunscreens
  • Serums
  • Day Creams
  • Essences
  • Exfoliators
  • Masks
  • Foundation
  • Oral Care
  • Night Creams
  • Starter Kits
  • Micellar Waters
  • Moisturisers
  • Neck Creams
  • Oils
  • Targeted Treatments
  • Toners
  • Tools & Devices
  • Supplements
  • Foot Treatments
  • Ampoules
  • Eye Care
  • BB & CC Creams
  • Body
  • Men
  • Gift Vouchers
  • Haircare
  • Hand & Nail

Shop All

Designed to mirror the structure of ceramides.

DERMANIQUE
Science

Key Ingredients

  • MicroDiPeptide²²⁹
  • Stem Cell Conditioning Media
  • GMOD™ Complex
  • Retinoids
  • Vitamin C
  • Salicylic Acid
  • Growth Factors
  • Alpha-Hydroxy Acids
  • Centella Asiatica
  • Azelaic Acid
  • Glycolic Acid
  • Hyaluronic Acid
  • Melasyl™
  • Polyhydroxy Acid (PHA)
  • Prickly Pear Seed Oil
  • Peptides
  • Co-enzyme Q10
  • Oat Kernel Extract
  • Extremozymes
  • Niacinamide
  • Glutathione
  • Kojic Acid
  • Ceramides
  • Panthenol
  • Iron Oxide
  • Pycnogenol®
  • Gluconolactone
  • NeoGlucosamine
  • Arbutin
  • Copper Tripeptides

Shop All

Read Dr Webster's Blog

ALL ABOUT UREA
Promotions
Skin Assessment
Learn
Podcast
Dr Ian Webster
Lift, Firm & Protect
Introducing two powerful new MartiDerm formulas clinically-proven to improve visible signs of skin ageing.
Explore now
cosmelan® 2
mesoestetic cosmelan® 2 homecare is a revolutionary treatment for hyperpigmentation delivering visible results across all skin phototypes.
Shop now
Huxley BioSIS 360
Huxley enters its anti-ageing era with two advanced new formulas designed to support environmentally-challenged skin.
Explore now
Effaclar Duo+M
Newly reformulated with Phylobioma that targets blemish-causing bacteria and helps restore microbiome balance.
Shop now
Jorgobé Multi-Peptide Lip Balm

Jorgobé Multi-Peptide Lip Balm

Jorgobé Multi-Peptide Lip Balm is an ultra-rich blend that deeply hydrates, restores, and plumps the lips with a glossy finish while enhancing volume and smoothing fine lines for a naturally fuller look. Suitable for all skin types. Key ingredients include Peptides, which stimulate collagen and hyaluronic acid production, enhancing lip volume and smoothing fine lines. Collagen Amino Acids, derived from algae, bind moisture for instant plumping and improved hydration. Volulip™ is an advanced formula that boosts lip shape, volume, and moisture by stimulating natural collagen and hyaluronic acid synthesis. A nourishing base of Castor, Avocado, Olive, and Coconut Oils, along with Shea and Mango Butter, ensures long-lasting hydration and protection. Fragrance-free. Dr Webster's Recommendation: Jorgobé Multi-Peptide Lip Balm is ideal for daily use or as an on-the-go treatment whenever your lips need a boost of hydration and a touch of gloss.
VIEW PRODUCT
Huxley BioSIS 360 Ampoule

Huxley BioSIS 360 Ampoule

Huxley BioSIS 360 Ampoule is a multi-benefit anti-ageing treatment that enhances skin elasticity, provides deep hydration, and improves skin texture for a firmer, more radiant complexion. Suitable for all skin types with ageing concerns, including sensitive skin. Key ingredients include iN-SIS5, a complex of Vitamin C derivatives and antioxidant-rich plant extracts known for their firming and skin-protective properties. Bouncy Thera-P™ contains Hyaluronic Acid and Ceramides to improve skin density and hydration. Collagen Tetra Pack is a blend of Hydrolysed Collagen that helps retain moisture while enhancing firmness and elasticity. Niacinamide (Vitamin B3) improves skin elasticity and uneven skin tone, while enhancing barrier function. Panthenol is a soothing humectant that pairs well with HA, delivering optimum results. Centella Asiatica (Gotu Kola) Leaf Extract has excellent moisturising benefits and anti-inflammatory properties. Fragrance-free. Dr Webster's Recommendation: Huxley BioSIS 360 Ampoule is a fast-absorbing, non-sticky ampoule that features a moisture-rich gel with melting capsules that deeply hydrate while targeting concerns like fine wrinkles and sagging skin. Containing powerful antioxidants, hydration and skin plumping ingredients, this unique gel is suitable anyone with ageing concerns related to environmental exposure and stress.
VIEW PRODUCT
MartiDerm Ultimate Antiox Serum

MartiDerm Ultimate Antiox Serum

MartiDerm Ultimate Antiox Serum is a powerful and revitalising antioxidant treatment that brightens, hydrates, and evens skin tone while minimising the appearance of wrinkles. Suitable for early ageing skin. Key ingredients include Antiox6 C Complex (a blend of Glutathione, Astaxanthin, Ergothioneine, Polyphenol, Vitamin E, and Vitamin C) that delivers both immediate and long-lasting protection while boosting hydration and luminosity. Proteum 89+ is MartiDerm’s exclusive Proteoglycan that is clinically proven to improve skin hydration and resilience, while helping to counteract UV-related ageing. Sodium Hyaluronate provides surface and deep hydration to reduce trans-epidermal water loss and improve skin elasticity. Contains a subtle fragrance. Dr Webster’s Recommendation: MartiDerm Ultimate Antiox Serum is an advanced multi-blend antioxidant formula that defends against environmental stressors while restoring radiance to dull or uneven skin. Its concentrated formula helps restore a smooth, radiant, and even-looking complexion.
VIEW PRODUCT

Top Sellers this Month

bioderma-sensibio-water-500ml-vb-1400px
Bioderma Sensibio H20 Cleanser LIMITED EDITION designed by Victoria Beckham 500ml
An effective micellar cleansing solution that respects the fragility of the skin.
R415.00
ADD VIEW
huxley-solid-perfum-sunset-fog-1400px
Huxley Solid Perfume; Sunset Fog
A solid fragrance that features a smooth, balm-like texture with a fresh scent.
R620.00
ADD VIEW
Kiehl's Expertly Clear Blemish-Treating and Preventing Lotion
Kiehl's Expertly Clear Blemish-Treating and Preventing Lotion

A hydrating & clarifying lotion that help smooth skin while preventing breakouts.

R600.00
ADD VIEW
cerave-intensive-moisturising-lotion-urea-1400px
CeraVe Intensive Moisturizing Lotion with 5% Urea
A fast-absorbing, reparative lotion that tackles dry, rough & uneven skin.
R360.00
ADD VIEW
Mustela Universal Balm
Mustela Universal Balm
A rich protective balm that deeply nourishes and repairs dry areas of the skin.
R350.00
ADD VIEW
Colorescience Total Protection Color Balm SPF 50 (Savanna)
Colorescience Total Protection Color Balm SPF 50 (Savanna)

A hydrating mineral balm for lips and cheeks with buildable tint.

R910.00
ADD VIEW
Biretix Isorepair Cream
Biretix Isorepair Cream
A hydrating and repairing cream suitable for dry, acne-prone, or sensitised skin.
R325.00
ADD VIEW
Thymuskin Classic Serum Gel 100ml
Thymuskin Classic Serum Gel 100ml

A targeted hair loss treatment for normal to oily hair.

R1,105.00
ADD VIEW
No products found

All products are Ready to Ship 📦 Our average nationwide delivery time is currently 2 working days.

Chat with our Skin Experts

Honest & personalised product advice

Lauren

SKIN THERAPIST

Spark a conversation

Taylor

SKIN THERAPIST

Spark a conversation

Lara

SKIN THERAPIST

Spark a conversation

Christi

SKIN THERAPIST

Spark a conversation

Trending Categories

EXCLUSIVES
GIFT VOUCHERS
NEW ARRIVALS
WINTER SETS
GROWTH FACTORS
PREGNANCY
DARK MARKS
SHOP ALL

Shop Specialist-Curated

Peace of mind care

Tools

Haircare

Eye care

Oral Care

Latest Reviews

Grace (verified owner)

What a wonderful, calming moisturising cleanser. I generally prefer foaming cleansers, but the Jorgobe Hydra Cleanser has a slight foam with a rich moisturising effect while still cleansing the skin thoroughly. It has calmed my redness and left my skin feeling plump and cleansed. Love the simple packaging with the pump bottle too. One pump goes a long way.

★★★★★ 5/5

Jorgobé Glycerin Hydra Cleanser

Ryan Miller (verified owner)

Have been using this since December of 2024, and the difference is noteworthy. It has become my retinol serum of choice. I would recommend it not only for the good quantity and quality of retinol but also for the other key ingredients.

★★★★★ 5/5

ZO Skin Health Wrinkle + Texture Repair 50ml

Nora (verified owner)

Love it! It helps brighten my skin post CO2 laser and doesn't cause irritation. C E Ferulic unfortunately broke me out - Serum 10 doesn't. It absorbs quickly and doesn't leave a sticky residue. My colleagues commented about my glowy skin. I'll definitely repurchase.

★★★★★ 5/5

SkinCeuticals Serum 10

Kim (verified owner)

My favourite moisturiser, ever. My mature skin just loves everything about it. I've used it for years.

★★★★★ 5/5

Huxley Anti-Gravity Cream

★★★★★ /5

Colorescience Total Protection Color Balm SPF 50 (Glow)

Latest Articles

All About Urea

Read More »
May 14, 2025
Why Skincare Matters for Teens

Why Skincare Matters for Teens

Read More »
February 25, 2025

The Benefits of Bakuchiol

Read More »
November 13, 2024

Dr Webster's Skin Assessment

Get Dermatologist recommendations or live chat with one of our skin therapists.

LEARN MORE

Free Samples
with every order

Plus get free & fast nationwide delivery on all orders over R750.

LEARN MORE
Shop by Top Range
  • SkinCeuticals
  • NeoStrata
  • MartiDerm
  • Huxley
  • Lamelle
  • pHformula
  • Melumé
  • ZO Skin Health
Customer Experience
  • Help Center
  • Become a Member
  • Video Consultations
  • Newsletter
  • Rx Products
  • DermaPoints Loyalty
  • Terms & Conditions
  • Clinical Studies
  • Gift Vouchers
About Us
  • Contact Us
  • Our Brands
  • Our Story
  • Podcast
  • Google Reviews
  • Distribution

Specialist online skincare store backed by a leading Dermatologist.

Facebook-f Instagram Spotify Apple

© Dermastore® 2025 All Rights Reserved

Rx

Dermastore® Rx labelled products require registration and a quick once-off multiple choice assessment.

Get Started

Learn more about Rx labelled products.

Already a member?

Login