Skip to content
Free delivery on all orders over R750
Click Here
Chat with qualified skin therapists
Click Here
Free samples with every order
Click Here
Explore free gifts & promotions
Click Here
Hello 👋
Shop by Product Type

Shop All

Ampoules
Baby
Barrier Creams
BB & CC Creams
Body
Cleansers
Day Creams
Essences
Exfoliators
Eye Care
Foot Treatments
Foundation
Gift Vouchers
Haircare
Hand & Nail
Masks
Men
Micellar Waters
Moisturisers
Neck Creams
Night Creams
Oils
Oral Care
Serums
Starter Kits
Sunscreens
Supplements
Targeted Treatments
Toners
Tools & Devices
Shop by Brand

Shop All

Melumé Skinscience
SkinCeuticals
Dr. Barbara Sturm
Huxley
NeoStrata®
Heliocare
Beaut™
Jorgobé
MartiDerm
Lamelle
iS Clinical
Hyaestic
PCA Skin
pHformula
ZO Skin Health
Kiehl's
mesoestetic
Obagi
La Roche-Posay
CeraVe
Exuviance
FEEV
Shop by Concern
Actinic Keratosis
Adult Acne
Atopic Eczema
Blackheads
Expression Lines
Eyelash & Eyebrow
Keratosis Pilaris
Lips
Perioral Dermatitis
Post-Acne Marks
Post-Treatment
Pregnancy
Psoriasis
Redness
Scars
Seborrhoeic Dermatitis
Stretch Marks
Shop by Science

Shop All

Retinoids
Vitamin C
Hyaluronic Acid
Azelaic Acid
Glycolic Acid
Arbutin
Peptides
Gluconolactone
Extremozymes
Growth Factors
Ceramides
Centella Asiatica
Iron Oxide
Niacinamide
Kojic Acid
Co-enzyme Q10
Shop by Skin Type
Dark Marks
Dry & Sensitive
Early Ageing, Fine Lines
Mature, Sun Damaged
Normal or Combination
Oily, Acne-Prone
Red, Rosacea-Prone
Shop by Age
Teen
60+
50s
40s
30s
20s
My Account
  • Become a Member
  • Promotions
  • Skin Assessment
  • Video Consultations
  • Learn
  • Dr Ian Webster
  • Contact Us

Introducing Video Consultations

Hyper-personalised one-on-one product advice with a qualified skin therapist.
Book a Session
  • Sign-In
R0.00 0 Cart
Brands

Featured Brands

  • Biretix
  • Melumé Skinscience
  • SkinCeuticals
  • Dr. Barbara Sturm
  • Huxley
  • NeoStrata®
  • Heliocare
  • Beaut™
  • Jorgobé
  • MartiDerm
  • Lamelle
  • Dermanique
  • iS Clinical
  • Hyaestic
  • PCA Skin
  • pHformula
  • ZO Skin Health
  • Kiehl's
  • mesoestetic
  • Obagi
  • Geske
  • La Roche-Posay
  • CeraVe
  • Colorescience
  • Exuviance
  • Endocare
  • Aveeno
  • Avène
  • Bioderma
  • ISDIN

Shop All

Triple action invisible photo protection.

PHFORMULA PRO DEFENCE³
Skin Type

Skin Type

  • Mature, Sun Damaged
  • Normal or Combination
  • Dark Marks
  • Early Ageing, Fine Lines
  • Dry & Sensitive
  • Oily, Acne-Prone
  • Red, Rosacea-Prone

Shop All

  • Age
Teen
60+
50s
40s
30s
20s

Skin Concern

  • Stretch Marks
  • Eyelash & Eyebrow
  • Actinic Keratosis
  • Adult Acne
  • Post-Acne Marks
  • Expression Lines
  • Perioral Dermatitis
  • Keratosis Pilaris
  • Seborrhoeic Dermatitis
  • Lips
  • Blackheads
  • Atopic Eczema
  • Post-Treatment
  • Pregnancy
  • Psoriasis
  • Redness
  • Scars

Shop All

Promoting hair strength, volume & a gorgeous glossy look.

HUXLEY
Product Type

Product Type

  • Baby
  • Barrier Creams
  • Cleansers
  • Sunscreens
  • Serums
  • Day Creams
  • Essences
  • Exfoliators
  • Masks
  • Foundation
  • Oral Care
  • Night Creams
  • Starter Kits
  • Micellar Waters
  • Moisturisers
  • Neck Creams
  • Oils
  • Targeted Treatments
  • Toners
  • Tools & Devices
  • Supplements
  • Foot Treatments
  • Ampoules
  • Eye Care
  • BB & CC Creams
  • Body
  • Men
  • Gift Vouchers
  • Haircare
  • Hand & Nail

Shop All

Designed to mirror the structure of ceramides.

DERMANIQUE
Science

Key Ingredients

  • GMOD™ Complex
  • Retinoids
  • Vitamin C
  • Salicylic Acid
  • Growth Factors
  • Alpha-Hydroxy Acids
  • Centella Asiatica
  • Azelaic Acid
  • Glycolic Acid
  • Hyaluronic Acid
  • Melasyl™
  • Polyhydroxy Acid (PHA)
  • Prickly Pear Seed Oil
  • Peptides
  • Co-enzyme Q10
  • Oat Kernel Extract
  • Extremozymes
  • Niacinamide
  • Glutathione
  • Kojic Acid
  • Ceramides
  • Panthenol
  • Iron Oxide
  • Pycnogenol®
  • Gluconolactone
  • NeoGlucosamine
  • Arbutin
  • Copper Tripeptides
  • Avocado
  • Sodium PCA

Shop All

Arbutin helps to treat all forms hyperpigmentation.

READ THE BLOG
Promotions
Skin Assessment
Learn
Podcast
Dr Ian Webster
bioderma-sensibio-defensive-serum-1400px.webp

Rx

Serums / Bioderma

Bioderma Sensibio Defensive Serum

★★★★★ 0/5

R715.00

Earn 358 DermaPoints

Soothing Moisturising Serum

Early Ageing

SOLD OUT
Add to cart
Description

Bioderma Sensibio Defensive Serum is a soothing moisturising concentrate that works against inflammaging caused by external aggressors. Suitable for early ageing and sensitive skin.

Key ingredients include Bioderma’s unique Defensive Technology and a Fucose polymer that helps soothe inflammation. Carnosine & Vitamin E  are two powerful antioxidants that protect skin against environmental damage and pollution. Tetrapeptide-10 boosts the synthesis of lipids, enzymes and proteins that form part of the skin barrier. Red Sage polyphenols provide a potent anti-inflammatory action. Tested under dermatological supervision. Fragrance-free.

Dr Webster’s Recommendation: Bioderma Sensibio Defensive Serum is a lightweight and easily absorbed serum that provides long-lasting hydration as well as antioxidant defence against external aggressors. Pollution, UV rays and dust particles can aggravate skin sensitivity and weaken the skin’s defences leading to inflammaging. This light-textured serum helps strengthen the skin barrier, soothing and restoring a healthy natural glow.

Summary

Strength: N/A

Size: 30ml

SPF: N/A

Fragrance-Free: Yes

Application: Face

Use: AM/PM

How to Use
  • Apply morning and evening to face and neck after cleansing, ideally with a Sensibio cleanser.
  • Allow to absorb and follow with suitable moisturiser.
  • Use a high factor, broad spectrum sunscreen, apply daily.
Key Ingredients
  • Peptides
  • Vitamin E
  • Carnosine

FULL INGREDIENTS / INCI: AQUA/WATER/UAE, GLYCERIN, BUTYLENE GLYCOL, C15-19 ALKANE, SQUALANE, CELLULOSE, C20-22 ALKYL PHOSPHATE, C20-22 ALCOHOLS, PENTYLENE GLYCOL, 1,2-HEXANEDIOL, CAPRYLYL GLYCOL, CARNOSINE, POLYACRYLATE CROSSPOLYMER-6, MALTODEXTRIN, XANTHAN GUM, MANNITOL, XYLITOL, TOCOPHEROL, SALVIA MILTIORRHIZA ROOT EXTRACT, RHAMNOSE, GUM-1 BIOSACCHARIDE CITRIC ACID, GLYCINE SOJA (SOYBEAN) OIL, HYDROLYZED HYALURONIC ACID, SODIUM HYDROXIDE, PALMITOYL TETRAPEPTIDE-10
Works Well With

Bioderma

Bioderma Sensibio Soothing Micellar Cleansing Gel

R315.00
Bioderma
Bioderma Sensibio Soothing Micellar Cleansing Gel
Gentle Foaming Wash Sensitive / Rosacea-prone Skin
R315.00
ADD
VIEW

Bioderma

Bioderma Sensibio AR+ Cream

R450.00
Bioderma
Bioderma Sensibio AR+ Cream
Anti-Redness Moisturiser Rosacea-Prone Skin
R450.00
ADD
VIEW

Bioderma

Bioderma Sensibio AR BB Cream SPF 30

R490.00
Bioderma
Bioderma Sensibio AR BB Cream SPF 30
Sensibio Red, Rosacea-Prone Skin
R490.00
ADD
VIEW

Customer Reviews

There are no reviews yet.

Be the first to review “Bioderma Sensibio Defensive Serum” Cancel reply

You must be logged in to post a review.

Video

Dr Webster also recommends

mesoestetic

mesoestetic skin balance

R2,675.00
mesoestetic
mesoestetic skin balance
Soothing Serum Concentrate Sensitive Skin
R2,675.00
ADD
VIEW

FEEV

FEEV Hyper-Intensive Conditioning Serum

R780.00
R620.00
FEEV
FEEV Hyper-Intensive Conditioning Serum
Rich Moisturising Emulsion Problematic Skin
R780.00
R620.00
ADD
VIEW

SkinCeuticals

SkinCeuticals Phyto Corrective

R1,590.00
SkinCeuticals
SkinCeuticals Phyto Corrective
A light, oil-free serum with botanical extracts to soothe and calm dry, irritated, and red skin.
R1,590.00
ADD
VIEW
Shop by Top Range
  • SkinCeuticals
  • NeoStrata
  • MartiDerm
  • Huxley
  • Lamelle
  • pHformula
  • Melumé
  • ZO Skin Health
Customer Experience
  • Help Center
  • Become a Member
  • Video Consultations
  • Newsletter
  • Rx Products
  • DermaPoints Loyalty
  • Terms & Conditions
  • Clinical Studies
  • Gift Vouchers
About Us
  • Contact Us
  • Our Brands
  • Our Story
  • Podcast
  • Google Reviews
  • Distribution

Specialist online skincare store backed by a leading Dermatologist.

Facebook-f Instagram Spotify Apple

© Dermastore® 2025 All Rights Reserved

Rx

Dermastore® Rx labelled products require registration and a quick once-off multiple choice assessment.

Get Started

Learn more about Rx labelled products.

Already a member?

Login