Skip to content
Free delivery on all orders over R750
Click Here
Chat with qualified skin therapists
Click Here
Free samples with every order
Click Here
Explore free gifts & promotions
Click Here
Hello 👋
Shop by Product Type

Shop All

Ampoules
Baby
Barrier Creams
BB & CC Creams
Body
Cleansers
Day Creams
Essences
Exfoliators
Eye Care
Foot Treatments
Foundation
Gift Vouchers
Haircare
Hand & Nail
Masks
Men
Micellar Waters
Moisturisers
Neck Creams
Night Creams
Oils
Oral Care
Serums
Starter Kits
Sunscreens
Supplements
Targeted Treatments
Toners
Tools & Devices
Shop by Brand

Shop All

Melumé Skinscience
SkinCeuticals
Dr. Barbara Sturm
Huxley
NeoStrata®
Heliocare
Beaut™
Jorgobé
MartiDerm
Lamelle
iS Clinical
Hyaestic
PCA Skin
pHformula
ZO Skin Health
Kiehl's
mesoestetic
Obagi
La Roche-Posay
CeraVe
Exuviance
FEEV
Shop by Concern
Actinic Keratosis
Adult Acne
Atopic Eczema
Blackheads
Expression Lines
Eyelash & Eyebrow
Keratosis Pilaris
Lips
Perioral Dermatitis
Post-Acne Marks
Post-Treatment
Pregnancy
Psoriasis
Redness
Scars
Seborrhoeic Dermatitis
Stretch Marks
Shop by Science

Shop All

Retinoids
Vitamin C
Hyaluronic Acid
Azelaic Acid
Glycolic Acid
Arbutin
Peptides
Gluconolactone
Extremozymes
Growth Factors
Ceramides
Centella Asiatica
Iron Oxide
Niacinamide
Kojic Acid
Co-enzyme Q10
Shop by Skin Type
Dark Marks
Dry & Sensitive
Early Ageing, Fine Lines
Mature, Sun Damaged
Normal or Combination
Oily, Acne-Prone
Red, Rosacea-Prone
Shop by Age
Teen
60+
50s
40s
30s
20s
My Account
  • Become a Member
  • Promotions
  • Skin Assessment
  • Video Consultations
  • Learn
  • Dr Ian Webster
  • Contact Us

Introducing Video Consultations

Hyper-personalised one-on-one product advice with a qualified skin therapist.
Book a Session
  • Sign-In
R0.00 0 Cart
Brands

Featured Brands

  • Biretix
  • Melumé Skinscience
  • SkinCeuticals
  • Dr. Barbara Sturm
  • Huxley
  • NeoStrata®
  • Heliocare
  • Beaut™
  • Jorgobé
  • MartiDerm
  • Lamelle
  • Dermanique
  • iS Clinical
  • Hyaestic
  • PCA Skin
  • pHformula
  • ZO Skin Health
  • Kiehl's
  • mesoestetic
  • Obagi
  • Geske
  • La Roche-Posay
  • CeraVe
  • Colorescience
  • Exuviance
  • Endocare
  • Aveeno
  • Avène
  • Bioderma
  • ISDIN

Shop All

Triple action invisible photo protection.

PHFORMULA PRO DEFENCE³
Skin Type

Skin Type

  • Mature, Sun Damaged
  • Normal or Combination
  • Dark Marks
  • Early Ageing, Fine Lines
  • Dry & Sensitive
  • Oily, Acne-Prone
  • Red, Rosacea-Prone

Shop All

  • Age
Teen
60+
50s
40s
30s
20s

Skin Concern

  • Stretch Marks
  • Eyelash & Eyebrow
  • Actinic Keratosis
  • Adult Acne
  • Post-Acne Marks
  • Expression Lines
  • Perioral Dermatitis
  • Keratosis Pilaris
  • Seborrhoeic Dermatitis
  • Lips
  • Blackheads
  • Atopic Eczema
  • Post-Treatment
  • Pregnancy
  • Psoriasis
  • Redness
  • Scars

Shop All

Promoting hair strength, volume & a gorgeous glossy look.

HUXLEY
Product Type

Product Type

  • Baby
  • Barrier Creams
  • Cleansers
  • Sunscreens
  • Serums
  • Day Creams
  • Essences
  • Exfoliators
  • Masks
  • Foundation
  • Oral Care
  • Night Creams
  • Starter Kits
  • Micellar Waters
  • Moisturisers
  • Neck Creams
  • Oils
  • Targeted Treatments
  • Toners
  • Tools & Devices
  • Supplements
  • Foot Treatments
  • Ampoules
  • Eye Care
  • BB & CC Creams
  • Body
  • Men
  • Gift Vouchers
  • Haircare
  • Hand & Nail

Shop All

Designed to mirror the structure of ceramides.

DERMANIQUE
Science

Key Ingredients

  • GMOD™ Complex
  • Retinoids
  • Vitamin C
  • Salicylic Acid
  • Growth Factors
  • Alpha-Hydroxy Acids
  • Centella Asiatica
  • Azelaic Acid
  • Glycolic Acid
  • Hyaluronic Acid
  • Melasyl™
  • Polyhydroxy Acid (PHA)
  • Prickly Pear Seed Oil
  • Peptides
  • Co-enzyme Q10
  • Oat Kernel Extract
  • Extremozymes
  • Niacinamide
  • Glutathione
  • Kojic Acid
  • Ceramides
  • Panthenol
  • Iron Oxide
  • Pycnogenol®
  • Gluconolactone
  • NeoGlucosamine
  • Arbutin
  • Copper Tripeptides
  • Avocado
  • Sodium PCA

Shop All

Arbutin helps to treat all forms hyperpigmentation.

READ THE BLOG
Promotions
Skin Assessment
Learn
Podcast
Dr Ian Webster
isdin-ureadin-ultra-20-antiroughness-cream-1400px.webp

Rx

Body / ISDIN

ISDIN Ureadin Ultra 20 Anti-roughness Cream

★★★★★ 5.00/5

R320.00

Earn 161 DermaPoints

Localised Body Cream

Very dry, rough and coarse skin

SOLD OUT
ADD TO CART
Description

ISDIN Ureadin Ultra 20 Anti-roughness Cream is an ultra-hydrating, emollient cream for very dry, rough and coarse skin. Helps Keratosis Pilaris on the outer arm (not underarm) and cracks and fissures on the fingers.

Key ingredients include patented 20% Urea ISDIN®, which acts as a keratolytic agent, helping to soften coarse and flaky skin. It also improves the integrity of the skin by encouraging skin barrier restoration, helping to alleviate itching caused by dryness. Dimethicone acts as a filmogenic occlusive that retains moisture close to the skin in severely dry areas.

Dr Webster’s Recommendation: Ureadin Ultra20 is a non-oily, fast-absorbing cream. It restores skin’s smoothness and eliminates hard skin, soothing it thanks to the exfoliant action of Urea ISDIN® which also retains water.

Summary

Strength: 20% Urea

Size: 100ml

SPF: None

Application: Body

Use: Once or twice a day

How to Use
  • Apply 1 or 2 times a day on clean and dry skin, focusing on the driest areas.
  • Massage gently until completely absorbed.
  • For best results, we recommend prolonged use.
  • Do not apply to the face.
  • Do not use on injured or irritated skin.
  • Do not use on the face, thin skin areas, mucous membranes or on open wounds.
Key Ingredients
  • Urea
  • Dimethicone

FULL INGREDIENTS / INCI: AQUA (WATER), UREA, ISOPROPYL MYRISTATE, PARAFFNUM LIQUIDUM (MINERAL OIL), GLYCERYL STEARATE, PEG-40 STEARATE, SORBITOL, CETEARYL ETHYLHEXANOATE, CETYL ALCOHOL, DIMETHICONE, GLYCINE, PHENOXYETHANOL, PERSEA GRATISSIMA (AVOCADO) OIL, CARBOMER, ALLANTOIN, PALMITIC ACID, STEARIC ACID, ACRYLATES / C10-30 ALKYL ACRYLATE CROSSPOLYMER, DISODIUM EDTA, ETHYLHEXYLGLYCERIN, PARFUM (FRAGRANCE), SODIUM HYDROXIDE, LIMONENE, HEXYL CINNAMAL, LACTIC ACID, ALPHA-ISOMETHYL IONONE, LINALOOL, BENZYL SALICYLATE, EUGENOL, CITRAL, HYDROXYCITRONELLAL, COUMARIN.
Works Well With

Customer Reviews

5

/5

Based on 02 rating(s)

5 Star
100%
2 review(s)
4 Star
0%
0 review(s)
3 Star
0%
0 review(s)
2 Star
0%
0 review(s)
1 Star
0%
0 review(s)

Reviewed by 02 customer(s)

Sort by

  • Hannah

    I have suffered with eczema my whole life and have managed to get it under control, except for my hands. This is my first time using this product and I can confirm that I have seen a massive difference! Leaves my hands silky smooth and reduced my dry spots!

    August 7, 2023
    Verified Review

    Helpful?

    Reply
  • Paige

    This is the first cream that i have used for Ketratosis Pilaris on my arms so I can’t compare it to other products that are targeted for this condition. However, I noticed an improvement on the rough texture and bumps disappeared, leaving my arms smooth.

    January 24, 2022
    Verified Review

    Helpful?

    Reply

Leave feedback about this Cancel reply

You must be logged in to post a review.

Video

Dr Webster also recommends

La Roche-Posay

La Roche-Posay Lipikar Lait Urea 5+ 400ml

R535.00
La Roche-Posay
La Roche-Posay Lipikar Lait Urea 5+ 400ml
Smoothing Body Lotion Rough & Flaky Skin
R535.00
ADD
VIEW
Shop by Top Range
  • SkinCeuticals
  • NeoStrata
  • MartiDerm
  • Huxley
  • Lamelle
  • pHformula
  • Melumé
  • ZO Skin Health
Customer Experience
  • Help Center
  • Become a Member
  • Video Consultations
  • Newsletter
  • Rx Products
  • DermaPoints Loyalty
  • Terms & Conditions
  • Clinical Studies
  • Gift Vouchers
About Us
  • Contact Us
  • Our Brands
  • Our Story
  • Podcast
  • Google Reviews
  • Distribution

Specialist online skincare store backed by a leading Dermatologist.

Facebook-f Instagram Spotify Apple

© Dermastore® 2025 All Rights Reserved

Rx

Dermastore® Rx labelled products require registration and a quick once-off multiple choice assessment.

Get Started

Learn more about Rx labelled products.

Already a member?

Login