Skip to content
Free delivery on all orders over R750
Click Here
Chat with qualified skin therapists
Click Here
Free samples with every order
Click Here
Explore free gifts & promotions
Click Here
Hello 👋
Shop by Product Type

Shop All

Ampoules
Baby
Barrier Creams
BB & CC Creams
Body
Cleansers
Day Creams
Essences
Exfoliators
Eye Care
Foot Treatments
Foundation
Gift Vouchers
Haircare
Hand & Nail
Masks
Men
Micellar Waters
Moisturisers
Neck Creams
Night Creams
Oils
Oral Care
Serums
Starter Kits
Sunscreens
Supplements
Targeted Treatments
Toners
Tools & Devices
Shop by Brand

Shop All

Melumé Skinscience
SkinCeuticals
Dr. Barbara Sturm
Huxley
NeoStrata®
Heliocare
Beaut™
Jorgobé
MartiDerm
Lamelle
iS Clinical
Hyaestic
PCA Skin
pHformula
ZO Skin Health
Kiehl's
mesoestetic
Obagi
La Roche-Posay
CeraVe
Exuviance
FEEV
Shop by Concern
Actinic Keratosis
Adult Acne
Atopic Eczema
Blackheads
Expression Lines
Eyelash & Eyebrow
Keratosis Pilaris
Lips
Perioral Dermatitis
Post-Acne Marks
Post-Treatment
Pregnancy
Psoriasis
Redness
Scars
Seborrhoeic Dermatitis
Stretch Marks
Shop by Science

Shop All

Retinoids
Vitamin C
Hyaluronic Acid
Azelaic Acid
Glycolic Acid
Arbutin
Peptides
Gluconolactone
Extremozymes
Growth Factors
Ceramides
Centella Asiatica
Iron Oxide
Niacinamide
Kojic Acid
Co-enzyme Q10
Shop by Skin Type
Dark Marks
Dry & Sensitive
Early Ageing, Fine Lines
Mature, Sun Damaged
Normal or Combination
Oily, Acne-Prone
Red, Rosacea-Prone
Shop by Age
Teen
60+
50s
40s
30s
20s
My Account
  • Become a Member
  • Promotions
  • Skin Assessment
  • Video Consultations
  • Learn
  • Dr Ian Webster
  • Contact Us

Introducing Video Consultations

Hyper-personalised one-on-one product advice with a qualified skin therapist.
Book a Session
  • Sign-In
R0.00 0 Cart
Brands

Featured Brands

  • Biretix
  • Melumé Skinscience
  • SkinCeuticals
  • Dr. Barbara Sturm
  • Huxley
  • NeoStrata®
  • Heliocare
  • Beaut™
  • Jorgobé
  • MartiDerm
  • Lamelle
  • Dermanique
  • iS Clinical
  • Hyaestic
  • PCA Skin
  • pHformula
  • ZO Skin Health
  • Kiehl's
  • mesoestetic
  • Obagi
  • Geske
  • La Roche-Posay
  • CeraVe
  • Colorescience
  • Exuviance
  • Endocare
  • Aveeno
  • Avène
  • Bioderma
  • ISDIN

Shop All

Triple action invisible photo protection.

PHFORMULA PRO DEFENCE³
Skin Type

Skin Type

  • Mature, Sun Damaged
  • Normal or Combination
  • Dark Marks
  • Early Ageing, Fine Lines
  • Dry & Sensitive
  • Oily, Acne-Prone
  • Red, Rosacea-Prone

Shop All

  • Age
Teen
60+
50s
40s
30s
20s

Skin Concern

  • Stretch Marks
  • Eyelash & Eyebrow
  • Actinic Keratosis
  • Adult Acne
  • Post-Acne Marks
  • Expression Lines
  • Perioral Dermatitis
  • Keratosis Pilaris
  • Seborrhoeic Dermatitis
  • Lips
  • Blackheads
  • Atopic Eczema
  • Post-Treatment
  • Pregnancy
  • Psoriasis
  • Redness
  • Scars

Shop All

Promoting hair strength, volume & a gorgeous glossy look.

HUXLEY
Product Type

Product Type

  • Baby
  • Barrier Creams
  • Cleansers
  • Sunscreens
  • Serums
  • Day Creams
  • Essences
  • Exfoliators
  • Masks
  • Foundation
  • Oral Care
  • Night Creams
  • Starter Kits
  • Micellar Waters
  • Moisturisers
  • Neck Creams
  • Oils
  • Targeted Treatments
  • Toners
  • Tools & Devices
  • Supplements
  • Foot Treatments
  • Ampoules
  • Eye Care
  • BB & CC Creams
  • Body
  • Men
  • Gift Vouchers
  • Haircare
  • Hand & Nail

Shop All

Designed to mirror the structure of ceramides.

DERMANIQUE
Science

Key Ingredients

  • GMOD™ Complex
  • Retinoids
  • Vitamin C
  • Salicylic Acid
  • Growth Factors
  • Alpha-Hydroxy Acids
  • Centella Asiatica
  • Azelaic Acid
  • Glycolic Acid
  • Hyaluronic Acid
  • Melasyl™
  • Polyhydroxy Acid (PHA)
  • Prickly Pear Seed Oil
  • Peptides
  • Co-enzyme Q10
  • Oat Kernel Extract
  • Extremozymes
  • Niacinamide
  • Glutathione
  • Kojic Acid
  • Ceramides
  • Panthenol
  • Iron Oxide
  • Pycnogenol®
  • Gluconolactone
  • NeoGlucosamine
  • Arbutin
  • Copper Tripeptides
  • Avocado
  • Sodium PCA

Shop All

Arbutin helps to treat all forms hyperpigmentation.

READ THE BLOG
Promotions
Skin Assessment
Learn
Podcast
Dr Ian Webster
mesoestetic-melan-tran3x-kit-new-1400px
mesoestetic-melan-tran3x-concentrate-1400px.webp
mesoestetic-melan-tran3x-gelcream-1400px.webp
mesoestetic-melan-130-spf50-1400px
mesoestetic-melan-tran3x-kit-new-1400px
mesoestetic-melan-tran3x-concentrate-1400px.webp
mesoestetic-melan-tran3x-gelcream-1400px.webp
mesoestetic-melan-130-spf50-1400px

Rx

Starter Kits / mesoestetic

mesoestetic melan tran3x kit

★★★★★ 4.57/5

R5,810.00

Earn 2905 DermaPoints

Treatment Kit

Hyperpigmentation

SOLD OUT
Add to cart
Description

mesoestetic melan tran3x kit combines three hero products that intensively treat hyperpigmentation (sun spots, post-inflammatory hyperpigmentation and melasma). Suitable for most skin types except sensitive or intolerant skin. Dry skins will likely require an additional moisturiser to complement the routine.

Kit includes (full-size products) – Save R500:

  • mesoestetic melan tran3x concentrate
  • mesoestetic melan tran3x gel-cream
  • mesoestetic mesoprotech melan 130 pigment control SPF 50+

Dr Webster’s Recommendation: mesoestetic melan tran3x kit combines targeted products to help reduce the production of melanin, resulting in the reduced appearance of superficial dark marks/hyperpigmentation. Tranexamic acid has demonstrated some impressive results and paired with Kojic Acid, Mandelic, Lactic and Salicylic Acids as well as Niacinamide and very high-factor, broad-spectrum sunscreen, offers a comprehensive pigmentation treatment program. Some products contain Mandelic Acid, which is derived from bitter almonds so if you have a nut allergy we do not recommend you use them. Consult your physician before use if you have an auto-immune disease.

Not indicated for use during pregnancy and lactation.

Summary

Strength: N/A

Size: Serum (30ml); Gel-cream (50ml); SPF (50ml)

SPF: 50+

Application: Face

Use: AM/PM

How to Use
  • mesoestetic melan tran3x concentrate
    Apply 3-4 drops using the dropper morning and evening. Spread evenly. Wait until absorbed and follow with melan tran3x gel-cream.
  • mesoestetic melan tran3x gel-cream
    Apply a thin layer all over your skin.
  • mesoestetic mesoprotech melan 130 pigment control
    Apply sufficient quantity (2mg/cm2 of skin) half an hour before exposure, on clean and dry skin. Reducing the amount of cream applied reduces the level of sun protection significantly. Reapply every 2 hours in case of direct sun exposure, after towel drying, bathing or sweating. Reapplication is essential to maintain the level of protection and effectiveness of the treatment. Avoid direct contact with eyes and mucous membranes , if necessary, rinse with plenty of water.
  • Store in a cool, dry place and keep out of the reach of children.
Key Ingredients
  • Salicylic Acid
  • Niacinamide
  • Kojic Acid
  • UVA & UVB Filters
  • Tranexamic Acid
  • Lactic Acid
  • Mandelic Acid

FULL INGREDIENTS / INCI: See individual products for full ingredients lists.
Works Well With

mesoestetic

mesoestetic glycolic + vitamin e + f ampoule (10 units)

R1,735.00
Rx
mesoestetic
mesoestetic glycolic + vitamin e + f ampoule (10 units)
Potent Boosting Treatment Imperfections & Skin Ageing
R1,735.00
ADD
VIEW

mesoestetic

mesoestetic brightening foam

R1,175.00
mesoestetic
mesoestetic brightening foam
Renewing Cleansing Foam Normal & Combination Skin
R1,175.00
ADD
VIEW

mesoestetic

mesoestetic melan recovery

R2,100.00
mesoestetic
mesoestetic melan recovery
Calming & Hydrating Moisturiser Dark Marks / Hyperigmentation
R2,100.00
ADD
VIEW

Customer Reviews

4.57

/5

Based on 07 rating(s)

5 Star
71.43%
5 review(s)
4 Star
14.29%
1 review(s)
3 Star
14.29%
1 review(s)
2 Star
0%
0 review(s)
1 Star
0%
0 review(s)

Reviewed by 07 customer(s)

Sort by

  • Thelma

    I have been using this product for more than a year. My skin has a glow but progress on enlightening the pigmentation is very slow but slowly clearing. I like concentrate pigmentation control as it hides the marks a bit.

    August 11, 2024
    Verified Review

    Helpful?

    Reply
  • Samantha

    Have been using this range for a year now. One of the best for pigmentation. It is light on the skin but effective. You have to use the serum before your moisturiser or night cream.

    July 27, 2022
    Verified Review

    Helpful?

    Reply
  • Chenell

    The concentrate is lovely but the gel-cream and sunblock are not as good. The gel-cream makes my skin smell weird and teh sunblock is very oily and leaves a residue. The concentrate is good but have not seen much of a difference on my post acne hyperpigmentation

    September 7, 2021
    Verified Review

    Helpful?

    Reply
  • Andri

    Absolutely love this kit. I’ve been struggling with pigmentation for while and after two months I can see a real difference! My skin texture has also improved. I will really recommend this kit – after trial and error and spending lots of money on various products – this combination works!! I was a bit hesitant to try the sunblock after reading the previous review about the tinted sunscreen. However, I have very light skin and it works perfectly.

    July 5, 2021
    Verified Review

    Helpful?

    Reply
  • Nikki

    I was pleasantly surprised about the difference this kit made to my pigmentation.
    Perfect kit to use after laser treatment to keep maintain stubborn pigmentation.

    May 30, 2021
    Verified Review

    Helpful?

    Reply
  • Deidre

    I have used the concentrate and gel-cream for 2 months now, and I’m very happy with the results. My pigmentation is very stubborn, and these products have definitely helped. My skin is clearer and smoother than it has been in years. However, be warned that the sunscreen is not suitable for very fair skins. The tint is quite dark and caramel in colour, more suitable for darker skin tones.

    April 17, 2021
    Verified Review

    Helpful?

    Reply
  • Barbara

    This kit has made such a difference to my pigmentation! I no longer have to cake foundation over my dark marks, only a light bb cream is more than enough now. So very impressed with this range. I will definitely carry on using these products. Big fan of the Mesoestetic range.

    November 16, 2020
    Verified Review

    Helpful?

    Reply

Leave feedback about this Cancel reply

You must be logged in to post a review.

Video

Dr Webster also recommends

MartiDerm

MartiDerm DSP Brightening Kit

R2,525.00
Rx
MartiDerm
MartiDerm DSP Brightening Kit
A brightening kit that helps reduce dark marks, sun spots, and melasma.
R2,525.00
ADD
VIEW

Neoretin

Neoretin Serum Booster + GelCream (Pack)

R2,450.00
Rx
Neoretin
Neoretin Serum Booster + GelCream (Pack)
Treatment Duo Dark Marks & Melasma
R2,450.00
ADD
VIEW

Lamelle

Lamelle Brighter Concentrate

R1,420.00
Rx
Lamelle
Lamelle Brighter Concentrate
A powerful pigmentation treatment that helps target stubborn dark marks.
R1,420.00
ADD
VIEW
Shop by Top Range
  • SkinCeuticals
  • NeoStrata
  • MartiDerm
  • Huxley
  • Lamelle
  • pHformula
  • Melumé
  • ZO Skin Health
Customer Experience
  • Help Center
  • Become a Member
  • Video Consultations
  • Newsletter
  • Rx Products
  • DermaPoints Loyalty
  • Terms & Conditions
  • Clinical Studies
  • Gift Vouchers
About Us
  • Contact Us
  • Our Brands
  • Our Story
  • Podcast
  • Google Reviews
  • Distribution

Specialist online skincare store backed by a leading Dermatologist.

Facebook-f Instagram Spotify Apple

© Dermastore® 2025 All Rights Reserved

Rx

Dermastore® Rx labelled products require registration and a quick once-off multiple choice assessment.

Get Started

Learn more about Rx labelled products.

Already a member?

Login