Skip to content
Free delivery on all orders over R750
Click Here
Chat with qualified skin therapists
Click Here
Free samples with every order
Click Here
Explore free gifts & promotions
Click Here
Hello 👋
Shop by Product Type

Shop All

Ampoules
Baby
Barrier Creams
BB & CC Creams
Body
Cleansers
Day Creams
Essences
Exfoliators
Eye Care
Foot Treatments
Foundation
Gift Vouchers
Haircare
Hand & Nail
Masks
Men
Micellar Waters
Moisturisers
Neck Treatments
Night Creams
Oils
Oral Care
Serums
Starter Kits
Sunscreens
Supplements
Targeted Treatments
Toners
Tools & Devices
Shop by Brand

Shop All

Purcell
Melumé Skinscience
SkinCeuticals
Huxley
NeoStrata®
Heliocare
Beaut™
Jorgobé
MartiDerm
Lamelle
iS Clinical
Hyaestic
pHformula
Kiehl's
mesoestetic
Obagi
La Roche-Posay
ISDIN
Shop by Concern
Actinic Keratosis
Adult Acne
Atopic Eczema
Blackheads
Expression Lines
Eyelash & Eyebrow
Keratosis Pilaris
Lips
Perioral Dermatitis
Post-Acne Marks
Post-Treatment
Pregnancy
Psoriasis
Redness
Scars
Seborrhoeic Dermatitis
Stretch Marks
Shop by Science

Shop All

Retinoids
Vitamin C
Hyaluronic Acid
Azelaic Acid
Glycolic Acid
Arbutin
Peptides
Gluconolactone
Extremozymes
Growth Factors
Ceramides
Centella Asiatica
Iron Oxide
Niacinamide
Kojic Acid
Co-enzyme Q10
Shop by Skin Type
Dark Marks
Dry & Sensitive
Early Ageing, Fine Lines
Mature, Sun Damaged
Normal or Combination
Oily, Acne-Prone
Red, Rosacea-Prone
Shop by Age
Teen
60+
50s
40s
30s
20s
My Account
  • Become a Member
  • Promotions
  • Skin Assessment
  • Video Consultations
  • Learn
  • Dr Ian Webster
  • Contact Us

Introducing Video Consultations

Hyper-personalised one-on-one product advice with a qualified skin therapist.
Book a Session
  • Sign-In
R1,180.00 2 Cart
Brands

Featured Brands

  • Purcell
  • Melumé Skinscience
  • SkinCeuticals
  • Huxley
  • NeoStrata®
  • Heliocare
  • Beaut™
  • Jorgobé
  • MartiDerm
  • Lamelle
  • Biretix
  • Dermanique
  • iS Clinical
  • Hyaestic
  • PCA Skin
  • pHformula
  • ZO Skin Health
  • Kiehl's
  • mesoestetic
  • Obagi
  • Geske
  • La Roche-Posay
  • CeraVe
  • Colorescience
  • Exuviance
  • Endocare
  • Aveeno
  • Avène
  • Bioderma
  • ISDIN

Shop All

A regenerating anti-ageing serum that reveals a smooth glow!

MARTIDERM NIGHT RENEW SERUM
Skin Type

Skin Type

  • Mature, Sun Damaged
  • Normal or Combination
  • Dark Marks
  • Early Ageing, Fine Lines
  • Dry & Sensitive
  • Oily, Acne-Prone
  • Red, Rosacea-Prone

Shop All

  • Age
Teen
60+
50s
40s
30s
20s

Skin Concern

  • Stretch Marks
  • Eyelash & Eyebrow
  • Actinic Keratosis
  • Adult Acne
  • Post-Acne Marks
  • Expression Lines
  • Perioral Dermatitis
  • Keratosis Pilaris
  • Seborrhoeic Dermatitis
  • Lips
  • Blackheads
  • Atopic Eczema
  • Post-Treatment
  • Pregnancy
  • Psoriasis
  • Redness
  • Scars

Shop All

Huxley’s Conditioning Collection

SHOP NOW
Product Type

Product Type

  • Baby
  • Barrier Creams
  • Cleansers
  • Sunscreens
  • Serums
  • Day Creams
  • Essences
  • Exfoliators
  • Masks
  • Foundation
  • Oral Care
  • Night Creams
  • Starter Kits
  • Micellar Waters
  • Moisturisers
  • Neck Treatments
  • Oils
  • Targeted Treatments
  • Toners
  • Tools & Devices
  • Supplements
  • Foot Treatments
  • Ampoules
  • Eye Care
  • BB & CC Creams
  • Body
  • Men
  • Gift Vouchers
  • Haircare
  • Hand & Nail

Shop All

Designed to mirror the structure of ceramides.

DERMANIQUE
Science

Key Ingredients

  • Cysteamine
  • MicroDiPeptide²²⁹®
  • Polyglutamic Acid
  • Stem Cell Conditioning Media
  • GMOD™ Complex
  • Retinoids
  • Vitamin C
  • Salicylic Acid
  • Growth Factors
  • Alpha-Hydroxy Acids
  • Centella Asiatica
  • Azelaic Acid
  • Glycolic Acid
  • Hyaluronic Acid
  • Melasyl™
  • Polyhydroxy Acid (PHA)
  • Prickly Pear Seed Oil
  • Peptides
  • Co-enzyme Q10
  • Oat Kernel Extract
  • Extremozymes
  • Niacinamide
  • Glutathione
  • Kojic Acid
  • Ceramides
  • Panthenol
  • Iron Oxide
  • Pycnogenol®
  • Gluconolactone
  • NeoGlucosamine

Shop All

Read Dr Webster's Blog

ALL ABOUT UREA
Promotions
Skin Assessment
Learn
Podcast
Dr Ian Webster

50s

Skincare in your 50s usually entails continuing everything from your 40s, including the regular use of retinoids and exfoliating acids, while supplementing the skin with peptide or growth factor-based creams or serums to help reduce the appearance of lines and wrinkles. During the menopausal phase, skin tends to dry out more, so ensure you are using a good barrier repair cream containing skin-identical ceramides and fatty acids daily.

Filter

Age
Skin Type
Product Type
Filter Products

Dermaceutic

Dermaceutic Tri Vita C30 Serum

R1,800.00
Rx
Dermaceutic
Dermaceutic Tri Vita C30 Serum
Concentrated 30% Vitamin C Serum Mature Ageing Skin
R1,800.00
ADD
VIEW

Bioderma

Bioderma Sensibio Soothing Micellar Cleansing Gel

R315.00
Bioderma
Bioderma Sensibio Soothing Micellar Cleansing Gel
A gentle foaming gel cleanser that soothes sensitive, rosacea-prone skin.
R315.00
ADD
VIEW

Dermaceutic

Dermaceutic Dual+ Anti-Blemish Serum

R1,765.00
Rx
Dermaceutic
Dermaceutic Dual+ Anti-Blemish Serum
Imperfection Correction Acne & Dark Marks
R1,765.00
ADD
VIEW

SkinCeuticals

SkinCeuticals Resveratrol B E

R3,300.00
SkinCeuticals
SkinCeuticals Resveratrol B E

A nighttime antioxidant that restores the skin's ability to repair and diminish visible ageing.

R3,300.00
ADD
VIEW

Kiehl's

Kiehl's Clearly Corrective Dark Spot Solution 30ml

R1,250.00
Kiehl's
Kiehl's Clearly Corrective Dark Spot Solution 30ml
Concentrated Brightening Serum Dark Marks & Uneven Tone
R1,250.00
ADD
VIEW

Colorescience

Colorescience Face Shield Flex (Medium)

R1,470.00
Colorescience
Colorescience Face Shield Flex (Medium)
A tinted mineral sunscreen for Fitzpatrick skin types II - III.
R1,470.00
ADD
VIEW

Avène

Avène Cleanance Women Smoothing Night Cream

R455.00
Avène
Avène Cleanance Women Smoothing Night Cream
Anti-blemish Night Cream. Adult Acne-Prone Skin.
R455.00
ADD
VIEW

Hyaestic

Hyaestic B5 Revital Serum

R960.00
Hyaestic
Hyaestic B5 Revital Serum
A soothing serum that helps calm, hydrate, and restore sensitive skin.
R960.00
ADD
VIEW

CeraVe

CeraVe Moisturising Cream 454g

R400.00
CeraVe
CeraVe Moisturising Cream 454g
Barrier-Restoring Cream Dry to Very Dry Skin
R400.00
ADD
VIEW

NeoStrata®

NeoStrata® Skin Active Hyaluronic Luminous Lift

R1,730.00
NeoStrata®
NeoStrata® Skin Active Hyaluronic Luminous Lift
A hydrating gel-cream that helps plump, firm, and even skin tone.
R1,730.00
ADD
VIEW

NeoStrata®

NeoStrata® Lip Wrinkle Repair

R520.00
NeoStrata®
NeoStrata® Lip Wrinkle Repair
A targeted lip treatment that helps smooth lines, hydrate, and plump lips.
R520.00
ADD
VIEW

ISDIN

ISDIN Ureadin Ultra 40 Gel Oil

R370.00
Rx
ISDIN
ISDIN Ureadin Ultra 40 Gel Oil
Ultra-Concentrated Conditioning Gel Rough, Localised Areas
R370.00
ADD
VIEW

Lamelle

Lamelle Dermaheal Cellular Repair Cream

R1,130.00
Lamelle
Lamelle Dermaheal Cellular Repair Cream
A medium-rich cream that helps address ageing with growth factor support.
R1,130.00
ADD
VIEW

Colorescience

Colorescience Total Protection Face Shield SPF 50 (Classic)

R1,290.00
Colorescience
Colorescience Total Protection Face Shield SPF 50 (Classic)
Full-Spectrum Mineral Protection All Skin Types
R1,290.00
ADD
VIEW

Melumé Skinscience

Melumé Micro-Encapsulated Retinol Stick

R1,980.00
Melumé Skinscience
Melumé Micro-Encapsulated Retinol Stick
A nourishing serum balm stick for targeted treatment for all ageing concerns.
R1,980.00
ADD
VIEW

Bioderma

Bioderma Sensibio H2O AR Micellar Water

R385.00
Bioderma
Bioderma Sensibio H2O AR Micellar Water
An anti-redness micellar water for sensitive, redness-prone skin.
R385.00
ADD
VIEW

MartiDerm

MartiDerm SHOTS Retinol Renew

R780.00
Rx
MartiDerm
MartiDerm SHOTS Retinol Renew
A fast-absorbing retinol serum that helps improve visible signs of ageing.
R780.00
ADD
VIEW

CeraVe

CeraVe Moisturising Lotion 236ml

R265.00
CeraVe
CeraVe Moisturising Lotion 236ml
Lightweight Body Lotion Normal & Dry Skin
R265.00
ADD
VIEW

SBR

SBR Protect Cream 100g

R255.00
SBR
SBR Protect Cream 100g

Lipid-Restoring Cream

Dry Skin

R255.00
ADD
VIEW

Bioderma

Bioderma Sensibio AR+ Bi-Serum

R750.00
Bioderma
Bioderma Sensibio AR+ Bi-Serum
A double-action serum reducing redness and firming ageing, rosacea-prone skin.
R750.00
ADD
VIEW

Dermaceutic

Dermaceutic Dermalift 5.0 Serum

R1,405.00
Rx
Dermaceutic
Dermaceutic Dermalift 5.0 Serum
Eye Lifting Serum Early & Mature Skin Ageing
R1,405.00
ADD
VIEW

Geske

Geske Sonic Thermo Facial Brush & Face-Lifter | 8 in 1

R1,295.00
Rx
Geske
Geske Sonic Thermo Facial Brush & Face-Lifter | 8 in 1
Cleansing, Firming & Toning Device Early & Mature Ageing Skin
R1,295.00
VIEW

iS Clinical

iS Clinical Poly-Vitamin Serum 15ml

R1,765.00
iS Clinical
iS Clinical Poly-Vitamin Serum 15ml
A revitalising serum that helps nourish, brighten, and improve overall skin health.
R1,765.00
ADD
VIEW

Colorescience

Colorescience Total Lash Mascara

R1,570.00
Colorescience
Colorescience Total Lash Mascara
Strengthen & Enhance Eyelash Mascara
R1,570.00
ADD
VIEW

Thymuskin

Thymuskin Regeneration Shampoo 200ml

R1,305.00
Thymuskin
Thymuskin Regeneration Shampoo 200ml

A scalp shampoo that helps reduce dandruff and soothes inflammation.

R1,305.00
ADD
VIEW

Lamelle

Lamelle Serra Restore Cream

R665.00
Lamelle
Lamelle Serra Restore Cream
A rich moisturiser that helps repair the barrier and soothe dry skin.
R665.00
ADD
VIEW

Endocare

Endocare Tensage Concentrate (10 units)

R1,100.00
Rx
Endocare
Endocare Tensage Concentrate (10 units)
Firming Dermal Regeneration Mature & Sun Damaged Skin
R1,100.00
ADD
VIEW

Bioderma

Bioderma Sensibio H20 Cleanser LIMITED EDITION designed by Victoria Beckham 500ml

R415.00
Bioderma
Bioderma Sensibio H20 Cleanser LIMITED EDITION designed by Victoria Beckham 500ml
A gentle micellar cleanser that soothes sensitive, irritated skin.
R415.00
ADD
VIEW

Huxley

Huxley Conditioning Cream

R550.00
Huxley
Huxley Conditioning Cream
A light yet silky cream that forms a protective moisture film for a soft, healthy glow.
R550.00
ADD
VIEW

MartiDerm

MartiDerm Micellar Cleansing Gel

R365.00
MartiDerm
MartiDerm Micellar Cleansing Gel
A gentle cleansing gel that helps purify skin while supporting the microbiome.
R365.00
ADD
VIEW

La Roche-Posay

La Roche-Posay Hyalu B5 Serum 30ml

R770.00
La Roche-Posay
La Roche-Posay Hyalu B5 Serum 30ml
Hydrate & Plumping Serum All Skin Types
R770.00
ADD
VIEW

PCA Skin

PCA Skin Hydrating Toner

R1,055.00
PCA Skin
PCA Skin Hydrating Toner
Hydrating pH-Balanced Toner Dry & Ageing Skin
R1,055.00
VIEW
1 2 3 4 5 … 26 Next
Shop by Top Range
  • SkinCeuticals
  • NeoStrata
  • MartiDerm
  • Huxley
  • Jorgobé
  • Lamelle
  • pHformula
  • Melumé Skinscience
  • Mesoestetic
Customer Experience
  • Help Center
  • Become a Member
  • Video Consultations
  • Newsletter
  • Rx Products
  • DermaPoints Loyalty
  • Terms & Conditions
  • Clinical Studies
  • Gift Vouchers
About Us
  • Contact Us
  • Our Brands
  • Our Story
  • Podcast
  • Google Reviews
  • Distribution

Specialist online skincare store backed by a leading Dermatologist.

Facebook-f Instagram Spotify Apple

© Dermastore® 2025 All Rights Reserved

< Back to all reviews
PCA Skin Hydrating Toner

Rx

Dermastore® Rx labelled products require registration and a quick once-off multiple choice assessment.

Get Started

Learn more about Rx labelled products.

Already a member?

Login