Skip to content
Free delivery on all orders over R750
Click Here
Chat with qualified skin therapists
Click Here
Free samples with every order
Click Here
Explore free gifts & promotions
Click Here
Hello 👋
Shop by Product Type

Shop All

Ampoules
Baby
Barrier Creams
BB & CC Creams
Body
Cleansers
Day Creams
Essences
Exfoliators
Eye Care
Foot Treatments
Foundation
Gift Vouchers
Haircare
Hand & Nail
Masks
Men
Micellar Waters
Moisturisers
Neck Creams
Night Creams
Oils
Oral Care
Serums
Starter Kits
Sunscreens
Supplements
Targeted Treatments
Toners
Tools & Devices
Shop by Brand

Shop All

Melumé Skinscience
SkinCeuticals
Dr. Barbara Sturm
Huxley
NeoStrata®
Heliocare
Beaut™
Jorgobé
MartiDerm
Lamelle
iS Clinical
Hyaestic
PCA Skin
pHformula
ZO Skin Health
Kiehl's
mesoestetic
Obagi
La Roche-Posay
CeraVe
Exuviance
FEEV
Shop by Concern
Actinic Keratosis
Adult Acne
Atopic Eczema
Blackheads
Expression Lines
Eyelash & Eyebrow
Keratosis Pilaris
Lips
Perioral Dermatitis
Post-Acne Marks
Post-Treatment
Pregnancy
Psoriasis
Redness
Scars
Seborrhoeic Dermatitis
Stretch Marks
Shop by Science

Shop All

Retinoids
Vitamin C
Hyaluronic Acid
Azelaic Acid
Glycolic Acid
Arbutin
Peptides
Gluconolactone
Extremozymes
Growth Factors
Ceramides
Centella Asiatica
Iron Oxide
Niacinamide
Kojic Acid
Co-enzyme Q10
Shop by Skin Type
Dark Marks
Dry & Sensitive
Early Ageing, Fine Lines
Mature, Sun Damaged
Normal or Combination
Oily, Acne-Prone
Red, Rosacea-Prone
Shop by Age
Teen
60+
50s
40s
30s
20s
My Account
  • Become a Member
  • Promotions
  • Skin Assessment
  • Video Consultations
  • Learn
  • Dr Ian Webster
  • Contact Us

Introducing Video Consultations

Hyper-personalised one-on-one product advice with a qualified skin therapist.
Book a Session
  • Sign-In
R320.00 1 Cart
Brands

Featured Brands

  • Biretix
  • Melumé Skinscience
  • SkinCeuticals
  • Dr. Barbara Sturm
  • Huxley
  • NeoStrata®
  • Heliocare
  • Beaut™
  • Jorgobé
  • MartiDerm
  • Lamelle
  • Dermanique
  • iS Clinical
  • Hyaestic
  • PCA Skin
  • pHformula
  • ZO Skin Health
  • Kiehl's
  • mesoestetic
  • Obagi
  • Geske
  • La Roche-Posay
  • CeraVe
  • Colorescience
  • Exuviance
  • Endocare
  • Aveeno
  • Avène
  • Bioderma
  • ISDIN

Shop All

Triple action invisible photo protection.

PHFORMULA PRO DEFENCE³
Skin Type

Skin Type

  • Mature, Sun Damaged
  • Normal or Combination
  • Dark Marks
  • Early Ageing, Fine Lines
  • Dry & Sensitive
  • Oily, Acne-Prone
  • Red, Rosacea-Prone

Shop All

  • Age
Teen
60+
50s
40s
30s
20s

Skin Concern

  • Stretch Marks
  • Eyelash & Eyebrow
  • Actinic Keratosis
  • Adult Acne
  • Post-Acne Marks
  • Expression Lines
  • Perioral Dermatitis
  • Keratosis Pilaris
  • Seborrhoeic Dermatitis
  • Lips
  • Blackheads
  • Atopic Eczema
  • Post-Treatment
  • Pregnancy
  • Psoriasis
  • Redness
  • Scars

Shop All

Promoting hair strength, volume & a gorgeous glossy look.

HUXLEY
Product Type

Product Type

  • Baby
  • Barrier Creams
  • Cleansers
  • Sunscreens
  • Serums
  • Day Creams
  • Essences
  • Exfoliators
  • Masks
  • Foundation
  • Oral Care
  • Night Creams
  • Starter Kits
  • Micellar Waters
  • Moisturisers
  • Neck Creams
  • Oils
  • Targeted Treatments
  • Toners
  • Tools & Devices
  • Supplements
  • Foot Treatments
  • Ampoules
  • Eye Care
  • BB & CC Creams
  • Body
  • Men
  • Gift Vouchers
  • Haircare
  • Hand & Nail

Shop All

Designed to mirror the structure of ceramides.

DERMANIQUE
Science

Key Ingredients

  • GMOD™ Complex
  • Retinoids
  • Vitamin C
  • Salicylic Acid
  • Growth Factors
  • Alpha-Hydroxy Acids
  • Centella Asiatica
  • Azelaic Acid
  • Glycolic Acid
  • Hyaluronic Acid
  • Melasyl™
  • Polyhydroxy Acid (PHA)
  • Prickly Pear Seed Oil
  • Peptides
  • Co-enzyme Q10
  • Oat Kernel Extract
  • Extremozymes
  • Niacinamide
  • Glutathione
  • Kojic Acid
  • Ceramides
  • Panthenol
  • Iron Oxide
  • Pycnogenol®
  • Gluconolactone
  • NeoGlucosamine
  • Arbutin
  • Copper Tripeptides
  • Avocado
  • Sodium PCA

Shop All

Arbutin helps to treat all forms hyperpigmentation.

READ THE BLOG
Promotions
Skin Assessment
Learn
Podcast
Dr Ian Webster

Dimethicone

Dimethicone is a type of silicone which is widely used in cosmetics, hair care and skin care. It is an occlusive agent that has a dual action in the skin to keep moisture in and aggressors out. It forms a physical layer over the skin that helps to prevent transepidermal water loss (TEWL) from the surface of the skin and it also helps to protect the skin from external aggressors such as irritants and toxins.

Filter

Age
Skin Type
Product Type
Filter Products

Obagi

Obagi CLENZIderm Therapeutic Moisturiser

R1,360.00
Obagi
Obagi CLENZIderm Therapeutic Moisturiser
CLENZIderm Daily moisturiser – Dry, Acne skin
R1,360.00
ADD
VIEW

ISDIN

ISDIN Isdinceutics Skin Drops (Bronze)

R1,060.00
ISDIN
ISDIN Isdinceutics Skin Drops (Bronze)
Adaptive Liquid Coverage All Skin Types
R1,060.00
VIEW

ISDIN

ISDIN Ureadin Ultra 20 Anti-roughness Cream

R320.00
Rx
ISDIN
ISDIN Ureadin Ultra 20 Anti-roughness Cream
Localised Body Cream Very dry, rough and coarse skin
R320.00
ADD
VIEW

ISDIN

ISDIN Ureadin Ultra 30 Exfoliating Cream

R270.00
Rx
ISDIN
ISDIN Ureadin Ultra 30 Exfoliating Cream
Exfoliating & Hydrating Cream Heels, Feet, Hands, Elbows & Knees
R270.00
ADD
VIEW

ISDIN

ISDIN Ureadin Ultra 40 Gel Oil

R370.00
Rx
ISDIN
ISDIN Ureadin Ultra 40 Gel Oil
Ultra-Concentrated Conditioning Gel Rough, Localised Areas
R370.00
ADD
VIEW

Lamelle

Lamelle Vita C 30 Cream

R1,230.00
Rx
Lamelle
Lamelle Vita C 30 Cream
An ultra-potent Vitamin C cream that helps protect and brighten ageing skin.
R1,230.00
ADD
VIEW

Obagi

Obagi ELASTIderm® Eye Cream

R2,135.00
Obagi
Obagi ELASTIderm® Eye Cream
ELASTIderm® Intense anti-ageing for firmer skin around the eyes.
R2,135.00
ADD
VIEW

La Roche-Posay

La Roche-Posay Effaclar Duo+ SPF 30

R355.00
La Roche-Posay
La Roche-Posay Effaclar Duo+ SPF 30
Corrective Treatment with SPF Blemish & Dark Marks
R355.00
ADD
VIEW

La Roche-Posay

La Roche-Posay Effaclar MAT

R360.00
La Roche-Posay
La Roche-Posay Effaclar MAT
Dual-Action Mattifying Moisturiser Oily & Sensitive Skin
R360.00
ADD
VIEW

mesoestetic

mesoestetic mesoprotech mineral fluid SPF 50+

R1,530.00
mesoestetic
mesoestetic mesoprotech mineral fluid SPF 50+
Physical Anti-Oxidant SPF Sensitive & Combination Skin
R1,530.00
ADD
VIEW

SkinCeuticals

SkinCeuticals Epidermal Repair

R2,010.00
SkinCeuticals
SkinCeuticals Epidermal Repair
A reparative treatment that supports the skin post-procedure when the barrier function is impaired.
R2,010.00
ADD
VIEW

La Roche-Posay

La Roche-Posay Lipikar Lait Urea 5+ 400ml

R535.00
La Roche-Posay
La Roche-Posay Lipikar Lait Urea 5+ 400ml
Smoothing Body Lotion Rough & Flaky Skin
R535.00
ADD
VIEW

La Roche-Posay

La Roche-Posay Anthelios XL Ultra-Light Invisible Body Mist SPF 50+

R470.00
La Roche-Posay
La Roche-Posay Anthelios XL Ultra-Light Invisible Body Mist SPF 50+
Sun Protection On the Go All Skin Types
R470.00
VIEW

La Roche-Posay

La Roche-Posay Anthelios Invisible Body Spray SPF 50+

R480.00
La Roche-Posay
La Roche-Posay Anthelios Invisible Body Spray SPF 50+
Sun Protection Body Spray All Skin Types
R480.00
VIEW

Colorescience

Colorescience Natural Pressed Foundation Light Ivory

R1,525.00
Colorescience
Colorescience Natural Pressed Foundation Light Ivory
Light Protective Foundation All Skin Types
R1,525.00
ADD
VIEW

Colorescience

Colorescience Natural Pressed Foundation Light Beige

R1,525.00
Colorescience
Colorescience Natural Pressed Foundation Light Beige
Light Protective Foundation All Skin Types
R1,525.00
ADD
VIEW
1 2 Next
Shop by Top Range
  • SkinCeuticals
  • NeoStrata
  • MartiDerm
  • Huxley
  • Lamelle
  • pHformula
  • Melumé
  • ZO Skin Health
Customer Experience
  • Help Center
  • Become a Member
  • Video Consultations
  • Newsletter
  • Rx Products
  • DermaPoints Loyalty
  • Terms & Conditions
  • Clinical Studies
  • Gift Vouchers
About Us
  • Contact Us
  • Our Brands
  • Our Story
  • Podcast
  • Google Reviews
  • Distribution

Specialist online skincare store backed by a leading Dermatologist.

Facebook-f Instagram Spotify Apple

© Dermastore® 2025 All Rights Reserved

Rx

Dermastore® Rx labelled products require registration and a quick once-off multiple choice assessment.

Get Started

Learn more about Rx labelled products.

Already a member?

Login