Skip to content
Free delivery on all orders over R750
Click Here
Chat with qualified skin therapists
Click Here
Free samples with every order
Click Here
Explore free gifts & promotions
Click Here
Hello 👋
Shop by Product Type

Shop All

Ampoules
Baby
Barrier Creams
BB & CC Creams
Body
Cleansers
Day Creams
Essences
Exfoliators
Eye Care
Foot Treatments
Foundation
Gift Vouchers
Haircare
Hand & Nail
Masks
Men
Micellar Waters
Moisturisers
Neck Treatments
Night Creams
Oils
Oral Care
Serums
Starter Kits
Sunscreens
Supplements
Targeted Treatments
Toners
Tools & Devices
Shop by Brand

Shop All

Purcell
Melumé Skinscience
SkinCeuticals
Huxley
NeoStrata®
Heliocare
Beaut™
Jorgobé
MartiDerm
Lamelle
iS Clinical
Hyaestic
pHformula
Kiehl's
mesoestetic
Obagi
La Roche-Posay
ISDIN
Shop by Concern
Actinic Keratosis
Adult Acne
Atopic Eczema
Blackheads
Expression Lines
Eyelash & Eyebrow
Keratosis Pilaris
Lips
Perioral Dermatitis
Post-Acne Marks
Post-Treatment
Pregnancy
Psoriasis
Redness
Scars
Seborrhoeic Dermatitis
Stretch Marks
Shop by Science

Shop All

Retinoids
Vitamin C
Hyaluronic Acid
Azelaic Acid
Glycolic Acid
Arbutin
Peptides
Gluconolactone
Extremozymes
Growth Factors
Ceramides
Centella Asiatica
Iron Oxide
Niacinamide
Kojic Acid
Co-enzyme Q10
Shop by Skin Type
Dark Marks
Dry & Sensitive
Early Ageing, Fine Lines
Mature, Sun Damaged
Normal or Combination
Oily, Acne-Prone
Red, Rosacea-Prone
Shop by Age
Teen
60+
50s
40s
30s
20s
My Account
  • Become a Member
  • Promotions
  • Skin Assessment
  • Video Consultations
  • Learn
  • Dr Ian Webster
  • Contact Us

Introducing Video Consultations

Hyper-personalised one-on-one product advice with a qualified skin therapist.
Book a Session
  • Sign-In
R1,020.00 2 Cart
Brands

Featured Brands

  • Purcell
  • Melumé Skinscience
  • SkinCeuticals
  • Huxley
  • NeoStrata®
  • Heliocare
  • Beaut™
  • Jorgobé
  • MartiDerm
  • Lamelle
  • Biretix
  • Dermanique
  • iS Clinical
  • Hyaestic
  • PCA Skin
  • pHformula
  • ZO Skin Health
  • Kiehl's
  • mesoestetic
  • Obagi
  • Geske
  • La Roche-Posay
  • CeraVe
  • Colorescience
  • Exuviance
  • Endocare
  • Aveeno
  • Avène
  • Bioderma
  • ISDIN

Shop All

A regenerating anti-ageing serum that reveals a smooth glow!

MARTIDERM NIGHT RENEW SERUM
Skin Type

Skin Type

  • Mature, Sun Damaged
  • Normal or Combination
  • Dark Marks
  • Early Ageing, Fine Lines
  • Dry & Sensitive
  • Oily, Acne-Prone
  • Red, Rosacea-Prone

Shop All

  • Age
Teen
60+
50s
40s
30s
20s

Skin Concern

  • Stretch Marks
  • Eyelash & Eyebrow
  • Actinic Keratosis
  • Adult Acne
  • Post-Acne Marks
  • Expression Lines
  • Perioral Dermatitis
  • Keratosis Pilaris
  • Seborrhoeic Dermatitis
  • Lips
  • Blackheads
  • Atopic Eczema
  • Post-Treatment
  • Pregnancy
  • Psoriasis
  • Redness
  • Scars

Shop All

Huxley’s Conditioning Collection

SHOP NOW
Product Type

Product Type

  • Baby
  • Barrier Creams
  • Cleansers
  • Sunscreens
  • Serums
  • Day Creams
  • Essences
  • Exfoliators
  • Masks
  • Foundation
  • Oral Care
  • Night Creams
  • Starter Kits
  • Micellar Waters
  • Moisturisers
  • Neck Treatments
  • Oils
  • Targeted Treatments
  • Toners
  • Tools & Devices
  • Supplements
  • Foot Treatments
  • Ampoules
  • Eye Care
  • BB & CC Creams
  • Body
  • Men
  • Gift Vouchers
  • Haircare
  • Hand & Nail

Shop All

Designed to mirror the structure of ceramides.

DERMANIQUE
Science

Key Ingredients

  • Cysteamine
  • MicroDiPeptide²²⁹®
  • Polyglutamic Acid
  • Stem Cell Conditioning Media
  • GMOD™ Complex
  • Retinoids
  • Vitamin C
  • Salicylic Acid
  • Growth Factors
  • Alpha-Hydroxy Acids
  • Centella Asiatica
  • Azelaic Acid
  • Glycolic Acid
  • Hyaluronic Acid
  • Melasyl™
  • Polyhydroxy Acid (PHA)
  • Prickly Pear Seed Oil
  • Peptides
  • Co-enzyme Q10
  • Oat Kernel Extract
  • Extremozymes
  • Niacinamide
  • Glutathione
  • Kojic Acid
  • Ceramides
  • Panthenol
  • Iron Oxide
  • Pycnogenol®
  • Gluconolactone
  • NeoGlucosamine

Shop All

Read Dr Webster's Blog

ALL ABOUT UREA
Promotions
Skin Assessment
Learn
Podcast
Dr Ian Webster

Niacinamide

Niacinamide is a potent cell-communicating ingredient that offers multiple benefits for impaired or ageing skin. Also known as Vitamin B3, and nicotinic acid, it is a naturally occurring vitamin that can be found in foods such as meats, nuts and mushrooms. Assuming skin is being protected from sun exposure, niacinamide can improve skin’s elasticity, dramatically enhance its barrier function, help improve discolorations, and revive skin’s healthy tone and texture.

Filter

Age
Skin Type
Product Type
Filter Products

SkinCeuticals

SkinCeuticals Metacell Renewal B3

R2,550.00
SkinCeuticals
SkinCeuticals Metacell Renewal B3

A multi-corrective moisturiser that targets early ageing, dullness, discolouration, and dryness.

R2,550.00
ADD
VIEW

SkinCeuticals

SkinCeuticals A.G.E Interrupter Advanced

R3,685.00
SkinCeuticals
SkinCeuticals A.G.E Interrupter Advanced
A powerhouse cream that helps correct the loss of volume and collagen for mature ageing.
R3,685.00
ADD
VIEW

La Roche-Posay

La Roche-Posay Effaclar Duo+M Tinted Deep Shade

R395.00
La Roche-Posay
La Roche-Posay Effaclar Duo+M Tinted Deep Shade
A dual-action tinted moisturiser that reduces blemishes and helps to prevent red or dark marks.
R395.00
ADD
VIEW

ZO Skin Health

ZO Skin Health Brightalive 50ml

R3,445.00
ZO Skin Health
ZO Skin Health Brightalive 50ml

A gentle brightening serum that helps fade dark spots and even skin tone.

R3,445.00
ADD
VIEW

Skin Republic

Skin Republic Retinol Hydrogel Under Eye Mask

R95.00
Skin Republic
Skin Republic Retinol Hydrogel Under Eye Mask
Anti-Ageing Eye Mask Lines, Dark Circles
R95.00
ADD
VIEW

MartiDerm

MartiDerm Acniover Active Cremigel

R435.00
MartiDerm
MartiDerm Acniover Active Cremigel
A mattifying cream gel that helps target blackheads, blemishes, and excess oil.
R435.00
ADD
VIEW

MartiDerm

MartiDerm Rosarepair Fluid Emulsion SPF30

R540.00
MartiDerm
MartiDerm Rosarepair Fluid Emulsion SPF30
A soothing emulsion that helps hydrate, calm, and visibly reduce redness.
R540.00
ADD
VIEW

Jorgobé

Jorgobé Niacinamide Body Lotion

R590.00
Jorgobé
Jorgobé Niacinamide Body Lotion
A fast-absorbing body lotion that helps even tone and boost elasticity.
R590.00
ADD
VIEW

La Roche-Posay

La Roche-Posay MELA B3 Set

R2,015.00
La Roche-Posay
La Roche-Posay MELA B3 Set

Target Hyperpigmentation

Save 15%

R2,015.00
VIEW

pHformula

pHformula MD MELA Active Recovery

R1,030.00
Rx
pHformula
pHformula MD MELA Active Recovery
A treatment serum that helps target and prevent pigmentation changes.
R1,030.00
ADD
VIEW

Lamelle

Lamelle Serra NSB Cream

R810.00
Lamelle
Lamelle Serra NSB Cream
A neuro-sensory cream that helps repair and soothe sensitive skin.
R810.00
ADD
VIEW

iS Clinical

iS Clinical Poly-Vitamin Serum 30ml

R2,815.00
Rx
iS Clinical
iS Clinical Poly-Vitamin Serum 30ml
A revitalising serum that helps nourish, brighten, and improve overall skin health.
R2,815.00
ADD
VIEW

ISDIN

ISDIN Isdinceutics Retinal Intense

R2,100.00
Rx
ISDIN
ISDIN Isdinceutics Retinal Intense
Rejuvenating Dual Phase Early Ageing Skin
R2,100.00
ADD
VIEW

Kiehl's

Kiehl's Super Multi-Corrective Eye Zone Treatment 14ml

R1,100.00
Kiehl's
Kiehl's Super Multi-Corrective Eye Zone Treatment 14ml
Invigorating Eye Cream Early & Mature Ageing
R1,100.00
ADD
VIEW

Dermaceutic

Dermaceutic Reveal 4X Advanced Eye Serum

R1,300.00
Dermaceutic
Dermaceutic Reveal 4X Advanced Eye Serum

Advanced Eye Serum

Dark Circles & Puffiness

R1,300.00
ADD
VIEW

iS Clinical

iS Clinical Poly-Vitamin Serum 15ml

R1,765.00
iS Clinical
iS Clinical Poly-Vitamin Serum 15ml
A revitalising serum that helps nourish, brighten, and improve overall skin health.
R1,765.00
ADD
VIEW

Kiehl's

Kiehl's Retinol Skin-Renewing Daily Micro-Dose Serum

R2,200.00
Rx
Kiehl's
Kiehl's Retinol Skin-Renewing Daily Micro-Dose Serum
Firming & Renewing Serum Early & Mature Ageing
R2,200.00
ADD
VIEW

Avène

Avène Hyaluron Activ B3 Night Cream

R740.00
Avène
Avène Hyaluron Activ B3 Night Cream
Regenerative Night Cream Early Ageing Skin
R740.00
ADD
VIEW

MartiDerm

MartiDerm DSP Brightening Kit

R2,525.00
Rx
MartiDerm
MartiDerm DSP Brightening Kit
A brightening kit that helps reduce dark marks, sun spots, and melasma.
R2,525.00
ADD
VIEW

MartiDerm

MartiDerm DSP Specific Body Areas

R750.00
MartiDerm
MartiDerm DSP Specific Body Areas
A targeted body cream for hyperpigmentation in sensitive areas.
R750.00
ADD
VIEW

La Roche-Posay

La Roche-Posay Lipikar Lait 400ml

R475.00
La Roche-Posay
La Roche-Posay Lipikar Lait 400ml
Lipid Replenishing Lotion Dry & Sensitive Skin
R475.00
ADD
VIEW

Huxley

Huxley BioSIS 360 Ampoule

R920.00
Huxley
Huxley BioSIS 360 Ampoule
A multi-benefit anti-ageing treatment that improves skin texture for a firmer, radiant complexion.
R920.00
ADD
VIEW

SkinCeuticals

SkinCeuticals P-Tiox Serum

R2,700.00
SkinCeuticals
SkinCeuticals P-Tiox Serum
A wrinkle-modulating peptide serum helps reduce the appearance of expression lines and sagging.
R2,700.00
ADD
VIEW

Colorescience

Colorescience Face Shield Flex (Deep)

R1,470.00
Colorescience
Colorescience Face Shield Flex (Deep)
A tinted mineral sunscreen for Fitzpatrick skin types IV - V.
R1,470.00
ADD
VIEW

Bioderma

Bioderma Pigmentbio C-Concentrate

R660.00
Bioderma
Bioderma Pigmentbio C-Concentrate
A brightening night serum targeting pigmentation and discoloration concerns.
R660.00
ADD
VIEW

CeraVe

CeraVe Foaming Cleanser 473ml

R360.00
CeraVe
CeraVe Foaming Cleanser 473ml
Foaming Gel Cleanser Normal & Combination Skin
R360.00
ADD
VIEW

ZO Skin Health

ZO Skin Health Brightalive 30ml

R2,220.00
ZO Skin Health
ZO Skin Health Brightalive 30ml
A gentle brightening serum that helps fade dark spots and even skin tone.
R2,220.00
ADD
VIEW

Huxley

Huxley Glow Awakening Cream

R630.00
Huxley
Huxley Glow Awakening Cream
A brightening moisturiser that protects and hydrates, leaving skin glowing.
R630.00
ADD
VIEW

SkinCeuticals

SkinCeuticals Advanced UV Brightening Sunscreen SPF 50

R1,400.00
SkinCeuticals
SkinCeuticals Advanced UV Brightening Sunscreen SPF 50
A lightweight sunscreen that brightens skin while offering broad-spectrum protection.
R1,400.00
ADD
VIEW

Dermastore®

Dermastore® Teen Acne Box

R1,435.00
Dermastore®
Dermastore® Teen Acne Box
Treatment Box Teen Acne
R1,435.00
ADD
VIEW

MartiDerm

MartiDerm DSP Cream SPF 50+

R680.00
Rx
MartiDerm
MartiDerm DSP Cream SPF 50+
A brightening sunscreen that helps treat and prevent all types of pigmentation.
R680.00
ADD
VIEW

pHformula

pHformula HYDRA Serum

R1,565.00
pHformula
pHformula HYDRA Serum
A hydrating serum that helps soothe, strengthen, and restore sensitive skin.
R1,565.00
ADD
VIEW
1 2 3 4 5 6 Next
Shop by Top Range
  • SkinCeuticals
  • NeoStrata
  • MartiDerm
  • Huxley
  • Jorgobé
  • Lamelle
  • pHformula
  • Melumé Skinscience
  • Mesoestetic
Customer Experience
  • Help Center
  • Become a Member
  • Video Consultations
  • Newsletter
  • Rx Products
  • DermaPoints Loyalty
  • Terms & Conditions
  • Clinical Studies
  • Gift Vouchers
About Us
  • Contact Us
  • Our Brands
  • Our Story
  • Podcast
  • Google Reviews
  • Distribution

Specialist online skincare store backed by a leading Dermatologist.

Facebook-f Instagram Spotify Apple

© Dermastore® 2025 All Rights Reserved

< Back to all reviews
pHformula HYDRA Serum

Rx

Dermastore® Rx labelled products require registration and a quick once-off multiple choice assessment.

Get Started

Learn more about Rx labelled products.

Already a member?

Login