Free delivery on all orders over R750
Click Here
Chat with qualified skin therapists
Click Here
Free samples with every order
Click Here
Explore free gifts & promotions
Click Here

Serums

Serums are generally lightweight, but super-efficient and packed with a high percentage active ingredients at optimum concentrations. They are the real workhorses behind any progressive skin care regimen. With smaller molecules they are easily absorbed by skin, and this often leads to more effective and more immediate results. After introducing a serum skin appearance and skin health are often rapidly improved.

Filter Products

ZO Skin Health

ZO Skin Health Firming Serum

R6,630.00
ZO Skin Health
ZO Skin Health Firming Serum

A firming serum that helps lift, define, and improve skin elasticity and tone.

R6,630.00
VIEW

ISDIN

ISDIN Isdinceutics Flavo-C Serum

R1,150.00
ISDIN
ISDIN Isdinceutics Flavo-C Serum
Daily Antioxidant Serum All Skin Types
R1,150.00
ADD
VIEW

Kiehl's

Kiehl's Clearly Corrective Dark Spot Solution 50ml

R1,850.00
Kiehl's
Kiehl's Clearly Corrective Dark Spot Solution 50ml
A targeted serum that visibly reduces dark spots and uneven tone.
R1,850.00
ADD
VIEW

iS Clinical

iS Clinical Retinol+ Emulsion 0.3

R2,570.00
Rx
iS Clinical
iS Clinical Retinol+ Emulsion 0.3
A potent retinol serum that helps smooth, firm, and brighten the skin.
R2,570.00
ADD
VIEW

Kiehl's

Kiehl's Ultra Pure High-Potency 9.8% Glycolic Acid Serum

R880.00
Rx
Kiehl's
Kiehl's Ultra Pure High-Potency 9.8% Glycolic Acid Serum
A refining serum that smooths texture and boosts skin renewal.
R880.00
ADD
VIEW

Lamelle

Lamelle Intensive GF Serum

R1,085.00
Rx
Lamelle
Lamelle Intensive GF Serum
A growth factor serum that helps remodel photo-damaged skin.
R1,085.00
ADD
VIEW

La Roche-Posay

La Roche-Posay Hyalu B5 Serum 50ml

R1,030.00
La Roche-Posay
La Roche-Posay Hyalu B5 Serum 50ml
Hydrate & Plumping Serum All Skin Types
R1,030.00
ADD
VIEW

pHformula

pHformula MD MELA Active Recovery

R1,030.00
Rx
pHformula
pHformula MD MELA Active Recovery
A treatment serum that helps target and prevent pigmentation changes.
R1,030.00
ADD
VIEW

Lamelle

Lamelle RA 5.0

R1,285.00
Rx
Lamelle
Lamelle RA 5.0
A high-performance 5% retinoid serum that helps prevent skin ageing.
R1,285.00
ADD
VIEW

Exuviance

Exuviance Clarifying and Renewing Serum

R920.00
Exuviance
Exuviance Clarifying and Renewing Serum

A clarifying and rejuvenating serum for oily skin prone to post-acne dark marks.

R920.00
ADD
VIEW

mesoestetic

mesoestetic melan tran3x concentrate

R2,775.00
mesoestetic
mesoestetic melan tran3x concentrate

An intensive serum targeting stubborn hyperpigmentation and dark marks.

 
R2,775.00
ADD
VIEW

MartiDerm

MartiDerm SHOTS Retinol Renew

R780.00
Rx
MartiDerm
MartiDerm SHOTS Retinol Renew
A fast-absorbing retinol serum that helps improve visible signs of ageing.
R780.00
ADD
VIEW

Avène

Avène Vitamin Activ Cg Radiance Corrector Serum

R770.00
Avène
Avène Vitamin Activ Cg Radiance Corrector Serum
Smoothing Brightening Serum Early Ageing Skin
R770.00
ADD
VIEW

MartiDerm

MartiDerm SHOTS Hyaluronic Firm

R780.00
MartiDerm
MartiDerm SHOTS Hyaluronic Firm
A refreshing gel-serum that helps boost hydration and firm the skin.
R780.00
ADD
VIEW

ISDIN

ISDIN Isdinceutics Retinal Intense

R2,100.00
Rx
ISDIN
ISDIN Isdinceutics Retinal Intense
Rejuvenating Dual Phase Early Ageing Skin
R2,100.00
ADD
VIEW

iS Clinical

iS Clinical Pro-Heal Serum Advance+ 30ml

R3,870.00
Rx
iS Clinical
iS Clinical Pro-Heal Serum Advance+ 30ml
A calming antioxidant serum that helps heal, protect, and strengthen sensitive skin.
R3,870.00
ADD
VIEW

Lamelle

Lamelle Correctives Vita-C Lipid Serum

R1,105.00
Lamelle
Lamelle Correctives Vita-C Lipid Serum
A potent Vitamin C serum that helps brighten even sensitive skin.
R1,105.00
ADD
VIEW

Kiehl's

Kiehl's Retinol Fast Release Night Serum

R2,400.00
Rx
Kiehl's
Kiehl's Retinol Fast Release Night Serum
A fast-acting retinol serum for wrinkles, dark marks and firmness.
R2,400.00
VIEW

Beaut™

Beaut™ Sunny Skin

R720.00
Beaut™
Beaut™ Sunny Skin
Antioxidant-rich serum that targets pigmentation and environmental stress.
R720.00
ADD
VIEW

ZO Skin Health

ZO Skin Health Exfoliation Accelerator

R2,080.00
ZO Skin Health
ZO Skin Health Exfoliation Accelerator

An exfoliating serum that helps smooth skin, boost renewal, and soothe irritation.

R2,080.00
ADD
VIEW

pHformula

pHformula VITA C Serum

R1,255.00
pHformula
pHformula VITA C Serum
A brightening serum that helps hydrate, illuminate, and boost skin radiance.
R1,255.00
ADD
VIEW

pHformula

pHformula MD CR Active Recovery

R1,030.00
Rx
pHformula
pHformula MD CR Active Recovery
A treatment serum that helps calm rosacea, redness, and strengthen skin barrier.
R1,030.00
ADD
VIEW

PCA Skin

PCA Skin Hyaluronic Acid Boosting Serum

R2,850.00
PCA Skin
PCA Skin Hyaluronic Acid Boosting Serum
Maximum Strength Hydrating Serum Dry & Dehydrated Skin
R2,850.00
ADD
VIEW

ZO Skin Health

ZO Skin Health Brightalive 50ml

R3,445.00
ZO Skin Health
ZO Skin Health Brightalive 50ml

A gentle brightening serum that helps fade dark spots and even skin tone.

R3,445.00
ADD
VIEW

iS Clinical

iS Clinical Hydra-Cool Serum 15ml

R1,565.00
iS Clinical
iS Clinical Hydra-Cool Serum 15ml
A cooling serum that helps hydrate, soothe, and refresh dull, irritated skin.
R1,565.00
ADD
VIEW

Kiehl's

Kiehl's Truly Targeted Blemish-Clearing Solution

R550.00
Kiehl's
Kiehl's Truly Targeted Blemish-Clearing Solution
An acne-clearing spot treatment creates a breathable seal that helps heal breakouts.
R550.00
ADD
VIEW

CeraVe

CeraVe Hydrating Hyaluronic Acid Serum

R500.00
CeraVe
CeraVe Hydrating Hyaluronic Acid Serum
Plumping & Hydrating Serum All Skin Types
R500.00
ADD
VIEW

MartiDerm

MartiDerm SHOTS VitaminC Antiox

R780.00
Rx
MartiDerm
MartiDerm SHOTS VitaminC Antiox
A melting balm with pure Vitamin C that helps protect and brighten skin.
R780.00
ADD
VIEW

mesoestetic

mesoestetic age element anti-wrinkle concentrate

R2,560.00
mesoestetic
mesoestetic age element anti-wrinkle concentrate

An anti-ageing serum that promotes collagen and reduces fine lines.

R2,560.00
ADD
VIEW

Jorgobé

Jorgobé Azelaic Acid Serum

R685.00
Jorgobé
Jorgobé Azelaic Acid Serum
A multi-functional serum that helps soothe, reduce blemishes, and dark marks.
R685.00
ADD
VIEW

Avène

Avène Hydrance Boost Serum

R500.00
Avène
Avène Hydrance Boost Serum
Daily Hydrating Serum Dry & Sensitive Skin
R500.00
ADD
VIEW

SkinCeuticals

SkinCeuticals Serum 10

R1,550.00
SkinCeuticals
SkinCeuticals Serum 10

A well-tolerated Vitamin C antioxidant serum that is ideal for dry, sensitive or intolerant skin.

R1,550.00
ADD
VIEW
1 2 3 4 5 6

Rx

Dermastore® Rx labelled products require registration and a quick once-off multiple choice assessment.

Get Started

Learn more about Rx labelled products.

Already a member?

Login