Skip to content
Free delivery on all orders over R750
Click Here
Chat with qualified skin therapists
Click Here
Free samples with every order
Click Here
Explore free gifts & promotions
Click Here
Hello 👋
Shop by Product Type

Shop All

Ampoules
Baby
Barrier Creams
BB & CC Creams
Body
Cleansers
Day Creams
Essences
Exfoliators
Eye Care
Foot Treatments
Foundation
Gift Vouchers
Haircare
Hand & Nail
Masks
Men
Micellar Waters
Moisturisers
Neck Creams
Night Creams
Oils
Oral Care
Serums
Starter Kits
Sunscreens
Supplements
Targeted Treatments
Toners
Tools & Devices
Shop by Brand

Shop All

Melumé Skinscience
SkinCeuticals
Dr. Barbara Sturm
Huxley
NeoStrata®
Heliocare
Beaut™
Jorgobé
MartiDerm
Lamelle
iS Clinical
Hyaestic
PCA Skin
pHformula
ZO Skin Health
Kiehl's
mesoestetic
Obagi
La Roche-Posay
CeraVe
Exuviance
FEEV
Shop by Concern
Actinic Keratosis
Adult Acne
Atopic Eczema
Blackheads
Expression Lines
Eyelash & Eyebrow
Keratosis Pilaris
Lips
Perioral Dermatitis
Post-Acne Marks
Post-Treatment
Pregnancy
Psoriasis
Redness
Scars
Seborrhoeic Dermatitis
Stretch Marks
Shop by Science

Shop All

Retinoids
Vitamin C
Hyaluronic Acid
Azelaic Acid
Glycolic Acid
Arbutin
Peptides
Gluconolactone
Extremozymes
Growth Factors
Ceramides
Centella Asiatica
Iron Oxide
Niacinamide
Kojic Acid
Co-enzyme Q10
Shop by Skin Type
Dark Marks
Dry & Sensitive
Early Ageing, Fine Lines
Mature, Sun Damaged
Normal or Combination
Oily, Acne-Prone
Red, Rosacea-Prone
Shop by Age
Teen
60+
50s
40s
30s
20s
My Account
  • Become a Member
  • Promotions
  • Skin Assessment
  • Video Consultations
  • Learn
  • Dr Ian Webster
  • Contact Us

Introducing Video Consultations

Hyper-personalised one-on-one product advice with a qualified skin therapist.
Book a Session
  • Sign-In
R0.00 0 Cart
Brands

Featured Brands

  • Biretix
  • Melumé Skinscience
  • SkinCeuticals
  • Dr. Barbara Sturm
  • Huxley
  • NeoStrata®
  • Heliocare
  • Beaut™
  • Jorgobé
  • MartiDerm
  • Lamelle
  • Dermanique
  • iS Clinical
  • Hyaestic
  • PCA Skin
  • pHformula
  • ZO Skin Health
  • Kiehl's
  • mesoestetic
  • Obagi
  • Geske
  • La Roche-Posay
  • CeraVe
  • Colorescience
  • Exuviance
  • Endocare
  • Aveeno
  • Avène
  • Bioderma
  • ISDIN

Shop All

Triple action invisible photo protection.

PHFORMULA PRO DEFENCE³
Skin Type

Skin Type

  • Mature, Sun Damaged
  • Normal or Combination
  • Dark Marks
  • Early Ageing, Fine Lines
  • Dry & Sensitive
  • Oily, Acne-Prone
  • Red, Rosacea-Prone

Shop All

  • Age
Teen
60+
50s
40s
30s
20s

Skin Concern

  • Stretch Marks
  • Eyelash & Eyebrow
  • Actinic Keratosis
  • Adult Acne
  • Post-Acne Marks
  • Expression Lines
  • Perioral Dermatitis
  • Keratosis Pilaris
  • Seborrhoeic Dermatitis
  • Lips
  • Blackheads
  • Atopic Eczema
  • Post-Treatment
  • Pregnancy
  • Psoriasis
  • Redness
  • Scars

Shop All

Promoting hair strength, volume & a gorgeous glossy look.

HUXLEY
Product Type

Product Type

  • Baby
  • Barrier Creams
  • Cleansers
  • Sunscreens
  • Serums
  • Day Creams
  • Essences
  • Exfoliators
  • Masks
  • Foundation
  • Oral Care
  • Night Creams
  • Starter Kits
  • Micellar Waters
  • Moisturisers
  • Neck Creams
  • Oils
  • Targeted Treatments
  • Toners
  • Tools & Devices
  • Supplements
  • Foot Treatments
  • Ampoules
  • Eye Care
  • BB & CC Creams
  • Body
  • Men
  • Gift Vouchers
  • Haircare
  • Hand & Nail

Shop All

Designed to mirror the structure of ceramides.

DERMANIQUE
Science

Key Ingredients

  • GMOD™ Complex
  • Retinoids
  • Vitamin C
  • Salicylic Acid
  • Growth Factors
  • Alpha-Hydroxy Acids
  • Centella Asiatica
  • Azelaic Acid
  • Glycolic Acid
  • Hyaluronic Acid
  • Melasyl™
  • Polyhydroxy Acid (PHA)
  • Prickly Pear Seed Oil
  • Peptides
  • Co-enzyme Q10
  • Oat Kernel Extract
  • Extremozymes
  • Niacinamide
  • Glutathione
  • Kojic Acid
  • Ceramides
  • Panthenol
  • Iron Oxide
  • Pycnogenol®
  • Gluconolactone
  • NeoGlucosamine
  • Arbutin
  • Copper Tripeptides
  • Avocado
  • Sodium PCA

Shop All

Arbutin helps to treat all forms hyperpigmentation.

READ THE BLOG
Promotions
Skin Assessment
Learn
Podcast
Dr Ian Webster
la-rocheposay-effaclar-ultra-concentrated-serum-1400px.webp

Rx

Serums / La Roche-Posay

La Roche-Posay Effaclar Ultra Concentrated Serum

★★★★★ 4.33/5

R640.00

Earn 320 DermaPoints

Targeted Corrective Serum

Oily & Acne-Prone Skin

SOLD OUT
ADD TO CART
Description

La Roche-Posay Effaclar Ultra Concentrated Serum is designed to improve overall skin texture, while simultaneously targeting blackheads, blemishes, and marks. Ideal for acne-prone skin with ageing concerns.

Key ingredients include Glycolic Acid,  Salicylic Acid, LHA (Lipo-Hydroxy Acid) which helps to unclog pores, and smooth the skin’s surface, and increase cellular regeneration overnight. Niacinamide is known to improve elasticity, and pigmentation and enhance skin barrier function. Due to its unique mineral composition, La Roche-Posay Thermal Spring Water has soothing properties that have been shown to reduce skin irritations. Contains a fragrance.

Dr Webster’s Recommendation: The Effaclar Serum formula contains complementary exfoliating ingredients that have been demonstrated to improve efficacy while soothing ingredients decrease skin irritations. This innovative formula is ideal for adult-acne patients as it will have anti-ageing benefits, whilst treating blackheads and blemishes. Exfoliation is key for unclogging pores, improving acne scarring, and brightening the skin’s overall complexion and appearance.

Safety during pregnancy not established. Consult with your physician regarding use during pregnancy or lactation.
Summary

Strength: 3.5% Glycolic Acid | 1.5% Salicylic Acid | 0.45% LHA | 1% HEPES | 1% Citric Acid | 2% Niacinamide | 2% Thermal Spring Water

Size: 30ml

SPF: None

Fragrance-Free: No

Application: Face

Use: PM

How to Use
  • Use once daily as part of your night routine.
  • Release pipet onto fingertips and press into skin, avoiding eye contour.
  • Avoid prolonged sun exposure and apply SPF daily while using this product
Key Ingredients
  • Salicylic Acid
  • Glycolic Acid
  • Niacinamide
  • Lipohydroxy Acid (LHA)
  • HEPES
  • La Roche-Posay Thermal Spring Water

FULL INGREDIENTS / INCI: AQUA / WATER, ALCOHOL DENAT., PROPANEDIOL, GLYCOLIC ACID, NIACINAMIDE, DIMETHYL ISOSORBIDE, PENTYLENE GLYCOL, SALICYLIC ACID, SODIUM HYDROXIDE, PEG-60 HYDROGENATED CASTOR OIL, HYDROXYETHYLPIPERAZINE ETHANE SULFONIC ACID, CITRIC ACID, PEG-30 GLYCERYL COCOATE, CAPRYLOYL SALICYLIC ACID, BIOSACCHARIDE GUM-1, MALTODEXTRIN, PHYTIC ACID, POLYQUATERNIUM-10, PARFUM / FRAGRANCE, B253155/1
Works Well With

La Roche-Posay

La Roche-Posay Anthelios UVMUNE 400 Tinted Fluid SPF 50+

R395.00
La Roche-Posay
La Roche-Posay Anthelios UVMUNE 400 Tinted Fluid SPF 50+
Tinted SPF Fluid All Skin Types
R395.00
ADD
VIEW

La Roche-Posay

La Roche-Posay Effaclar Foaming Gel 200ml

R315.00
La Roche-Posay
La Roche-Posay Effaclar Foaming Gel 200ml
Purifying Foaming Cleanser Combination & Oily Skin
R315.00
ADD
VIEW

La Roche-Posay

La Roche-Posay Effaclar Duo+ SPF 30

R355.00
La Roche-Posay
La Roche-Posay Effaclar Duo+ SPF 30
Corrective Treatment with SPF Blemish & Dark Marks
R355.00
ADD
VIEW

Customer Reviews

4.33

/5

Based on 09 rating(s)

5 Star
55.56%
5 review(s)
4 Star
22.22%
2 review(s)
3 Star
22.22%
2 review(s)
2 Star
0%
0 review(s)
1 Star
0%
0 review(s)

Reviewed by 09 customer(s)

Sort by

  • Candice

    Amazing product. Leaves my skin smooth. No tiny bumps on my nose. Slightly evened my spots. It’s a must have.

    August 9, 2023
    Verified Review

    Helpful?

    Reply
  • Anne-mari

    I can say this, it does help with break outs if used regularly, I have less hormonal acne on my chin and my blackheads are less. Stings a bit as my skin is sensitive but it doesn’t burn. Very cost effective solution.

    October 31, 2022
    Verified Review

    Helpful?

    Reply
  • Mandy

    Age:47 female
    Skin: Tends to be oily. Prone to blemishes and blackheads

    I love this stuff! I use it every night & am on my second bottle.
    It’s transformed my perimenopausal skin.

    Would love to know if I can use it with a retinol..

    October 19, 2022
    Verified Review

    Helpful?

    Reply
  • Carmen

    Great product but do not believe it would be suitable for sensitive skin. It clears out beautifully from beneath the skin but might sting some individuals.

    June 7, 2022
    Verified Review

    Helpful?

    Reply
  • Cealagh

    I have problems with blackheads so that was my main selling point but my skin burned when I used this. So not for those with sensitive skin but I gave it to my brother who said it was great and helped a lot with his blackheads and oil buildup.

    March 28, 2022
    Verified Review

    Helpful?

    Reply
  • Carien

    This product has transformed my problematic acne-prone skin. Works so well !

    June 21, 2021
    Verified Review

    Helpful?

    Reply
  • Neirne

    Great product. I use it with Effaclar Duo + and it has done wonders for my problematic skin.

    May 2, 2021
    Verified Review

    Helpful?

    Reply
  • Kaitlyn

    Enjoying this product, easy to use and the consistency is great!

    January 26, 2021
    Verified Review

    Helpful?

    Reply
  • Carika

    Love the product, will definitely repurchase it!

    January 16, 2021
    Verified Review

    Helpful?

    Reply

Leave feedback about this Cancel reply

You must be logged in to post a review.

Video

Dr Webster also recommends

Lamelle

Lamelle Clarity Corrective PM Plus

R885.00
Rx
Lamelle
Lamelle Clarity Corrective PM Plus
A nighttime moisturiser that helps soothe and heal active acne-prone skin.
R885.00
ADD
VIEW

SkinCeuticals

SkinCeuticals Blemish + Age Defense Serum

R2,010.00
Rx
SkinCeuticals
SkinCeuticals Blemish + Age Defense Serum

An exfoliating serum that reduces acne-causing bacteria, minimises blotchiness and evens skin tone.

R2,010.00
ADD
VIEW
Shop by Top Range
  • SkinCeuticals
  • NeoStrata
  • MartiDerm
  • Huxley
  • Lamelle
  • pHformula
  • Melumé
  • ZO Skin Health
Customer Experience
  • Help Center
  • Become a Member
  • Video Consultations
  • Newsletter
  • Rx Products
  • DermaPoints Loyalty
  • Terms & Conditions
  • Clinical Studies
  • Gift Vouchers
About Us
  • Contact Us
  • Our Brands
  • Our Story
  • Podcast
  • Google Reviews
  • Distribution

Specialist online skincare store backed by a leading Dermatologist.

Facebook-f Instagram Spotify Apple

© Dermastore® 2025 All Rights Reserved

Rx

Dermastore® Rx labelled products require registration and a quick once-off multiple choice assessment.

Get Started

Learn more about Rx labelled products.

Already a member?

Login