Skip to content
Free delivery on all orders over R750
Click Here
Chat with qualified skin therapists
Click Here
Free samples with every order
Click Here
Explore free gifts & promotions
Click Here
Hello 👋
Shop by Product Type

Shop All

Ampoules
Baby
Barrier Creams
BB & CC Creams
Body
Cleansers
Day Creams
Essences
Exfoliators
Eye Care
Foot Treatments
Foundation
Gift Vouchers
Haircare
Hand & Nail
Masks
Men
Micellar Waters
Moisturisers
Neck Creams
Night Creams
Oils
Oral Care
Serums
Starter Kits
Sunscreens
Supplements
Targeted Treatments
Toners
Tools & Devices
Shop by Brand

Shop All

Melumé Skinscience
SkinCeuticals
Dr. Barbara Sturm
Huxley
NeoStrata®
Heliocare
Beaut™
Jorgobé
MartiDerm
Lamelle
iS Clinical
Hyaestic
PCA Skin
pHformula
ZO Skin Health
Kiehl's
mesoestetic
Obagi
La Roche-Posay
CeraVe
Exuviance
FEEV
Shop by Concern
Actinic Keratosis
Adult Acne
Atopic Eczema
Blackheads
Expression Lines
Eyelash & Eyebrow
Keratosis Pilaris
Lips
Perioral Dermatitis
Post-Acne Marks
Post-Treatment
Pregnancy
Psoriasis
Redness
Scars
Seborrhoeic Dermatitis
Stretch Marks
Shop by Science

Shop All

Retinoids
Vitamin C
Hyaluronic Acid
Azelaic Acid
Glycolic Acid
Arbutin
Peptides
Gluconolactone
Extremozymes
Growth Factors
Ceramides
Centella Asiatica
Iron Oxide
Niacinamide
Kojic Acid
Co-enzyme Q10
Shop by Skin Type
Dark Marks
Dry & Sensitive
Early Ageing, Fine Lines
Mature, Sun Damaged
Normal or Combination
Oily, Acne-Prone
Red, Rosacea-Prone
Shop by Age
Teen
60+
50s
40s
30s
20s
My Account
  • Become a Member
  • Promotions
  • Skin Assessment
  • Video Consultations
  • Learn
  • Dr Ian Webster
  • Contact Us

Introducing Video Consultations

Hyper-personalised one-on-one product advice with a qualified skin therapist.
Book a Session
  • Sign-In
R7,780.00 2 Cart
Brands

Featured Brands

  • Biretix
  • Melumé Skinscience
  • SkinCeuticals
  • Dr. Barbara Sturm
  • Huxley
  • NeoStrata®
  • Heliocare
  • Beaut™
  • Jorgobé
  • MartiDerm
  • Lamelle
  • Dermanique
  • iS Clinical
  • Hyaestic
  • PCA Skin
  • pHformula
  • ZO Skin Health
  • Kiehl's
  • mesoestetic
  • Obagi
  • Geske
  • La Roche-Posay
  • CeraVe
  • Colorescience
  • Exuviance
  • Endocare
  • Aveeno
  • Avène
  • Bioderma
  • ISDIN

Shop All

Triple action invisible photo protection.

PHFORMULA PRO DEFENCE³
Skin Type

Skin Type

  • Mature, Sun Damaged
  • Normal or Combination
  • Dark Marks
  • Early Ageing, Fine Lines
  • Dry & Sensitive
  • Oily, Acne-Prone
  • Red, Rosacea-Prone

Shop All

  • Age
Teen
60+
50s
40s
30s
20s

Skin Concern

  • Stretch Marks
  • Eyelash & Eyebrow
  • Actinic Keratosis
  • Adult Acne
  • Post-Acne Marks
  • Expression Lines
  • Perioral Dermatitis
  • Keratosis Pilaris
  • Seborrhoeic Dermatitis
  • Lips
  • Blackheads
  • Atopic Eczema
  • Post-Treatment
  • Pregnancy
  • Psoriasis
  • Redness
  • Scars

Shop All

Promoting hair strength, volume & a gorgeous glossy look.

HUXLEY
Product Type

Product Type

  • Baby
  • Barrier Creams
  • Cleansers
  • Sunscreens
  • Serums
  • Day Creams
  • Essences
  • Exfoliators
  • Masks
  • Foundation
  • Oral Care
  • Night Creams
  • Starter Kits
  • Micellar Waters
  • Moisturisers
  • Neck Creams
  • Oils
  • Targeted Treatments
  • Toners
  • Tools & Devices
  • Supplements
  • Foot Treatments
  • Ampoules
  • Eye Care
  • BB & CC Creams
  • Body
  • Men
  • Gift Vouchers
  • Haircare
  • Hand & Nail

Shop All

Designed to mirror the structure of ceramides.

DERMANIQUE
Science

Key Ingredients

  • GMOD™ Complex
  • Retinoids
  • Vitamin C
  • Salicylic Acid
  • Growth Factors
  • Alpha-Hydroxy Acids
  • Centella Asiatica
  • Azelaic Acid
  • Glycolic Acid
  • Hyaluronic Acid
  • Melasyl™
  • Polyhydroxy Acid (PHA)
  • Prickly Pear Seed Oil
  • Peptides
  • Co-enzyme Q10
  • Oat Kernel Extract
  • Extremozymes
  • Niacinamide
  • Glutathione
  • Kojic Acid
  • Ceramides
  • Panthenol
  • Iron Oxide
  • Pycnogenol®
  • Gluconolactone
  • NeoGlucosamine
  • Arbutin
  • Copper Tripeptides
  • Avocado
  • Sodium PCA

Shop All

Arbutin helps to treat all forms hyperpigmentation.

READ THE BLOG
Promotions
Skin Assessment
Learn
Podcast
Dr Ian Webster
zo-skin-health-retinol-skin-brightener-1-1400px.webp

Rx

Serums / ZO Skin Health

ZO Skin Health Retinol Skin Brightener 1% 50ml

★★★★★ 0/5

R4,400.00

Earn 2201 DermaPoints

High-Strength Brightening Serum

Ageing & Dark Marks

SOLD OUT
ADD TO CART
Description

ZO Skin Health Retinol Skin Brightener is a high-strength Retinol serum that targets key signs of skin ageing, whilst brightening a dull, uneven skin tone. Suitable for mature ageing skin with superficial pigmentation.

Key ingredients include 1.0% Retinol that stimulates cellular renewal and collagen production for smoother, brighter-looking skin. Ascorbyl Glucoside (Vitamin C) has a brightening effect, helping to protect skin from free radical damage. It also protects and repairs cells damaged by UV exposure. A Glutathione and N-acetyl Glucosamine complex combats the appearance of new age spots and uneven skin tone. Stachys Officinalis helps to reduce the appearance of pigmentation caused by melanogenesis. Vitamin C & Vitamin E synergistically protect against oxidative stress and the harmful effects of pollution. Dermatologist-developed. Fragrance-free.

Dr Webster’s Recommendation: ZO Retinol Skin Brightener is a micro-encapsulated Retinol that helps to break up surface pigmentation and promote cellular turnover.  An innovative brightening technology utilises a multi-prong approach to inhibit the overproduction of melanin. It also reduces the potentially sensitizing effects of retinol, whilst providing antioxidant protection to prevent future damage. If more moisture is required, ZO Skin Health Renewal Crème can be applied over this serum. Use a high-factor, broad-spectrum sunscreen during the day. Not indicated for use during pregnancy.

Summary

Strength: 1% Retinol

Size: 50ml

SPF: N/A

Fragrance-Free: Yes

Application: Face

Use: PM

How to Use
  • After cleansing and toning, apply to the face, avoiding the eye area and the neck.
  • Begin by limiting use to twice a week, gradually increasing application frequency to every other night, and then advancing to each evening or as tolerated.
  • If more moisture is required, ZO Renewal Cream can be applied over this serum.
  • Mild irritation may initially be experienced and is not a sign of a negative complication.
  • This product is indicated for use in the evening only.
  • Daily broad spectrum sun protection is critical while using this product.
Key Ingredients
  • Retinoids
  • Vitamin C
  • Glutathione
  • Ascorbyl Glucoside
  • N-Acetyl Glucosamine
  • Vitamin E

FULL INGREDIENTS / INCI: AQUA/WATER/EAU, CETEARYL ISONONANOATE, CYCLOPENTASILOXANE, GLYCERIN, PRUNUS AMYGDALUS DULCIS (SWEET ALMOND) OLEOSOMES, CYCLOHEXASILOXANE, CETEARYL ALCOHOL, STEARETH-20, CETYL ALCOHOL, PENTYLENE GLYCOL, ASCORBYL GLUCOSIDE, POLYSORBATE 20, RETINOL, PROPYLHEPTYL CAPRYLATE, ACETYL GLUCOSAMINE, CETEARYL GLUCOSIDE, LECITHIN, ACRYLAMIDE/AMMONIUM ACRYLATE COPOLYMER, ALCOHOL, 1,2-HEXANEDIOL, CAPRYLYL GLYCOL, CARBOMER, GLUTATHIONE, NYLON-12, POLYSORBATE 80, SODIUM HYDROXIDE, POLYISOBUTENE, ASCORBYL PALMITATE, TOCOPHERYL ACETATE, DISODIUM EDTA, MALTODEXTRIN, PRUNUS ARMENIACA (APRICOT) KERNEL OIL, LAVANDULA ANGUSTIFOLIA (LAVENDER) OIL, STACHYS OFFICINALIS FLOWER/LEAF/STEM EXTRACT, PELARGONIUM GRAVEOLENS FLOWER OIL, LINALOOL, LIMONENE, GERANIOL, COUMARIN, CITRONELLOL, CITRAL, ZEA MAYS (CORN) OIL, SOY ISOFLAVONES, BETA-CAROTENE, BHT, BHA, POTASSIUM SORBATE, SODIUM METABISULFITE, SODIUM SULFITE.
Works Well With

ZO Skin Health

ZO Skin Health Daily Power Defense 50ml

R5,580.00
Rx
ZO Skin Health
ZO Skin Health Daily Power Defense 50ml
High-Potency Antioxidant Early & Mature Ageing
R5,580.00
ADD
VIEW

ZO Skin Health

ZO Skin Health Renewal Crème

R3,890.00
Rx
ZO Skin Health
ZO Skin Health Renewal Crème
Hydrating Repairing Moisturiser Normal & Combination Skin
R3,890.00
ADD
VIEW

ZO Skin Health

ZO Skin Health Retinol Skin Brightener 0.5%

R3,800.00
Rx
ZO Skin Health
ZO Skin Health Retinol Skin Brightener 0.5%
Mid-Strength Brightening Serum Hyperpigmentation
R3,800.00
ADD
VIEW

Customer Reviews

There are no reviews yet.

Be the first to review “ZO Skin Health Retinol Skin Brightener 1% 50ml” Cancel reply

You must be logged in to post a review.

Video

Dr Webster also recommends

SkinCeuticals

SkinCeuticals Retinol 1.0

R2,530.00
Rx
SkinCeuticals
SkinCeuticals Retinol 1.0
An advanced nighttime treatment to help reduce fine lines, wrinkles, and skin discolouration.
R2,530.00
ADD
VIEW

Dermaceutic

Dermaceutic Mela Cream

R2,110.00
Rx
Dermaceutic
Dermaceutic Mela Cream
Targeted Treatment Dark Marks / Hyperpigmentation / Melasma
R2,110.00
ADD
VIEW
Shop by Top Range
  • SkinCeuticals
  • NeoStrata
  • MartiDerm
  • Huxley
  • Lamelle
  • pHformula
  • Melumé
  • ZO Skin Health
Customer Experience
  • Help Center
  • Become a Member
  • Video Consultations
  • Newsletter
  • Rx Products
  • DermaPoints Loyalty
  • Terms & Conditions
  • Clinical Studies
  • Gift Vouchers
About Us
  • Contact Us
  • Our Brands
  • Our Story
  • Podcast
  • Google Reviews
  • Distribution

Specialist online skincare store backed by a leading Dermatologist.

Facebook-f Instagram Spotify Apple

© Dermastore® 2025 All Rights Reserved

Rx

Dermastore® Rx labelled products require registration and a quick once-off multiple choice assessment.

Get Started

Learn more about Rx labelled products.

Already a member?

Login