Skip to content
Free delivery on all orders over R750
Click Here
Chat with qualified skin therapists
Click Here
Free samples with every order
Click Here
Explore free gifts & promotions
Click Here
Hello 👋
Shop by Product Type

Shop All

Ampoules
Baby
Barrier Creams
BB & CC Creams
Body
Cleansers
Day Creams
Essences
Exfoliators
Eye Care
Foot Treatments
Foundation
Gift Vouchers
Haircare
Hand & Nail
Masks
Men
Micellar Waters
Moisturisers
Neck Creams
Night Creams
Oils
Oral Care
Serums
Starter Kits
Sunscreens
Supplements
Targeted Treatments
Toners
Tools & Devices
Shop by Brand

Shop All

Melumé Skinscience
SkinCeuticals
Dr. Barbara Sturm
Huxley
NeoStrata®
Heliocare
Beaut™
Jorgobé
MartiDerm
Lamelle
iS Clinical
Hyaestic
PCA Skin
pHformula
ZO Skin Health
Kiehl's
mesoestetic
Obagi
La Roche-Posay
CeraVe
Exuviance
FEEV
Shop by Concern
Actinic Keratosis
Adult Acne
Atopic Eczema
Blackheads
Expression Lines
Eyelash & Eyebrow
Keratosis Pilaris
Lips
Perioral Dermatitis
Post-Acne Marks
Post-Treatment
Pregnancy
Psoriasis
Redness
Scars
Seborrhoeic Dermatitis
Stretch Marks
Shop by Science

Shop All

Retinoids
Vitamin C
Hyaluronic Acid
Azelaic Acid
Glycolic Acid
Arbutin
Peptides
Gluconolactone
Extremozymes
Growth Factors
Ceramides
Centella Asiatica
Iron Oxide
Niacinamide
Kojic Acid
Co-enzyme Q10
Shop by Skin Type
Dark Marks
Dry & Sensitive
Early Ageing, Fine Lines
Mature, Sun Damaged
Normal or Combination
Oily, Acne-Prone
Red, Rosacea-Prone
Shop by Age
Teen
60+
50s
40s
30s
20s
My Account
  • Become a Member
  • Promotions
  • Skin Assessment
  • Video Consultations
  • Learn
  • Dr Ian Webster
  • Contact Us

Introducing Video Consultations

Hyper-personalised one-on-one product advice with a qualified skin therapist.
Book a Session
  • Sign-In
R0.00 0 Cart
Brands

Featured Brands

  • Biretix
  • Melumé Skinscience
  • SkinCeuticals
  • Dr. Barbara Sturm
  • Huxley
  • NeoStrata®
  • Heliocare
  • Beaut™
  • Jorgobé
  • MartiDerm
  • Lamelle
  • Dermanique
  • iS Clinical
  • Hyaestic
  • PCA Skin
  • pHformula
  • ZO Skin Health
  • Kiehl's
  • mesoestetic
  • Obagi
  • Geske
  • La Roche-Posay
  • CeraVe
  • Colorescience
  • Exuviance
  • Endocare
  • Aveeno
  • Avène
  • Bioderma
  • ISDIN

Shop All

Triple action invisible photo protection.

PHFORMULA PRO DEFENCE³
Skin Type

Skin Type

  • Mature, Sun Damaged
  • Normal or Combination
  • Dark Marks
  • Early Ageing, Fine Lines
  • Dry & Sensitive
  • Oily, Acne-Prone
  • Red, Rosacea-Prone

Shop All

  • Age
Teen
60+
50s
40s
30s
20s

Skin Concern

  • Stretch Marks
  • Eyelash & Eyebrow
  • Actinic Keratosis
  • Adult Acne
  • Post-Acne Marks
  • Expression Lines
  • Perioral Dermatitis
  • Keratosis Pilaris
  • Seborrhoeic Dermatitis
  • Lips
  • Blackheads
  • Atopic Eczema
  • Post-Treatment
  • Pregnancy
  • Psoriasis
  • Redness
  • Scars

Shop All

Promoting hair strength, volume & a gorgeous glossy look.

HUXLEY
Product Type

Product Type

  • Baby
  • Barrier Creams
  • Cleansers
  • Sunscreens
  • Serums
  • Day Creams
  • Essences
  • Exfoliators
  • Masks
  • Foundation
  • Oral Care
  • Night Creams
  • Starter Kits
  • Micellar Waters
  • Moisturisers
  • Neck Creams
  • Oils
  • Targeted Treatments
  • Toners
  • Tools & Devices
  • Supplements
  • Foot Treatments
  • Ampoules
  • Eye Care
  • BB & CC Creams
  • Body
  • Men
  • Gift Vouchers
  • Haircare
  • Hand & Nail

Shop All

Designed to mirror the structure of ceramides.

DERMANIQUE
Science

Key Ingredients

  • GMOD™ Complex
  • Retinoids
  • Vitamin C
  • Salicylic Acid
  • Growth Factors
  • Alpha-Hydroxy Acids
  • Centella Asiatica
  • Azelaic Acid
  • Glycolic Acid
  • Hyaluronic Acid
  • Melasyl™
  • Polyhydroxy Acid (PHA)
  • Prickly Pear Seed Oil
  • Peptides
  • Co-enzyme Q10
  • Oat Kernel Extract
  • Extremozymes
  • Niacinamide
  • Glutathione
  • Kojic Acid
  • Ceramides
  • Panthenol
  • Iron Oxide
  • Pycnogenol®
  • Gluconolactone
  • NeoGlucosamine
  • Arbutin
  • Copper Tripeptides
  • Avocado
  • Sodium PCA

Shop All

Arbutin helps to treat all forms hyperpigmentation.

READ THE BLOG
Promotions
Skin Assessment
Learn
Podcast
Dr Ian Webster
skinceuticals-glycolic-10-renew-overnight-1400px.webp

Rx

Night Creams / SkinCeuticals

SkinCeuticals Glycolic 10 Renew Overnight

★★★★★ 5.00/5

R1,790.00

Earn 895 DermaPoints

A potent nightly treatment formulated to target fine lines, wrinkles, and dullness.

SOLD OUT
ADD TO CART
Description

SkinCeuticals Glycolic 10 Renew Overnight is a nightly anti-ageing, corrective cream that accelerates cellular turnover, and noticeably improves dull skin, leaving it radiant and glowing with regular use. It refines uneven texture and tone, usually associated with sun damage. Suitable for all skin types except sensitive and rosacea-prone skin.

Key ingredients include Glycolic Acid formulated at 14% with a pH of 3.5 to deliver a true 10% active value to the skin. Derived from sugar cane, this fruit acid dissolves the cellular bonds to release dead and dehydrated cells on the surface of the skin. It accelerates desquamation (shedding), stimulating new cell regeneration which results in improved texture, tone, and a brighter complexion. Phytic Acid has a unique molecular structure that provides comprehensive exfoliation and it also promotes skin clarity. A soothing complex includes a combination of natural oils and botanicals including Jojoba and Sunflower seed oil to form a protective, breathable layer that helps to lock in the hydration and provide comfort. Fragrance-free.

Dr. Webster’s Recommendation: Glycolic acid is clinically proven to improve skin ageing. As the skin ages, there is a decrease in cellular turnover and this usually occurs when the skin is damaged due to excessive sun exposure together with the natural ageing process. Making use of the small Glycolic Acid molecule, SkinCeuticals Glycolic 10 Renew has been formulated to deliver an optimized concentration that penetrates the skin efficiently, helping it shed old skin cells that cause dullness and dryness. With regular use, it promotes clarity and brightness and it helps the skin to retain will help the skin to retain its youthful glow. Do not use this product on the same night as Retinol or any other exfoliating product – rather alternate nights to avoid irritation. It cannot be used in pregnancy or during lactation.

Summary

Strength: 10% Glycolic Acid (Free Acid Value)

Size: 50ml

SPF: None

Fragrance-Free: Yes

Application: Face, Neck

Use: PM

How to Use
  • Caution: Do not use this product together with Retinol or any other exfoliating product (AHAs) as the skin could become irritated. Rather alternate use - Retinol one night and this product the next night.
  • Use the SkinCeuticals Glycolic 10 Renew Overnight at night after cleansing.
  • Apply an even, pea-sized layer over entire face and neck. Avoid the eye area.
  • After one week, increase use to every evening or alternate evenings if using Retinol.
  • SUNBURN ALERT: This product contains an AHA that may increase your skins sensitivity to the sun.
  • Always use with a daytime antioxidant serum & a high factor, broad spectrum sunscreen every day as part of your anti-ageing regimen.
Key Ingredients
  • Glycolic Acid
  • Sunflower Seed Oil
  • Jojoba Oil
  • Phytic Acid

FULL INGREDIENTS / INCI: AQUA/WATER, GLYCOLIC ACID, DICAPRYLYL CARBONATE, DIMETHICONE, SODIUM HYDROXIDE, BUTYLENE GLYCOL, PROPANEDIOL, GLYCERIN, PHYTIC ACID, CETYL PEG/PPG-10/1 DIMETHICONE, ALUMINUM STARCH OCTENYLSUCCINATE, NYLON-12, POLYGLYCERYL-4 ISOSTEARATE, MAGNESIUM SULFATE, JOJOBA ESTERS, PHENOXYETHANOL, HELIANTHUS ANNUUS SEED CERA/SUNFLOWER SEED WAX, CAPRYLYL GLYCOL, DISODIUM EDTA, SALICYLIC ACID, ACACIA DECURRENS FLOWER CERA/ACACIA DECURRENS FLOWER WAX, POLYGLYCERIN-3, TOCOPHEROL, PENTAERYTHRITYL TETRA-DI-T-BUTYL HYDROXYHYDROCINNAMATE, D212791/1 ACL: 6038698 CNP: 6048108 CN : 1866073
Works Well With

SkinCeuticals

SkinCeuticals Phloretin CF

R3,100.00
SkinCeuticals
SkinCeuticals Phloretin CF
A high-potency antioxidant Vitamin C serum that offers superior protection, ideal for dark marks.
R3,100.00
ADD
VIEW

SkinCeuticals

SkinCeuticals Gentle Cleanser Cream

R850.00
SkinCeuticals
SkinCeuticals Gentle Cleanser Cream
Soothing Creamy Cleanser Sensitive & Dry Skin
R850.00
ADD
VIEW

SkinCeuticals

SkinCeuticals Physical Fusion UV Defense SPF 50

R1,050.00
SkinCeuticals
SkinCeuticals Physical Fusion UV Defense SPF 50
An advanced, lightweight, 100% mineral sunscreen offering broad-spectrum protection.
R1,050.00
ADD
VIEW

Customer Reviews

5

/5

Based on 03 rating(s)

5 Star
100%
3 review(s)
4 Star
0%
0 review(s)
3 Star
0%
0 review(s)
2 Star
0%
0 review(s)
1 Star
0%
0 review(s)

Reviewed by 03 customer(s)

Sort by

  • Al

    An amazing product; leaves my skin feeling refreshed. I saw the difference in my skin after 3 weeks of use.

    December 8, 2022
    Verified Review

    Helpful?

    Reply
  • Lucienne

    I have a mature, sun damaged skin and have been alternating SkinCeuticals Glycolic 10 OverNight with SkinCeuticals Retinol 0.5 for several months now. I am finally starting to love my skin again. My only regret is not having had this when I was younger. No more fine lines, oiliness or breakouts. Just a word of caution. You need to introduce these products slowly and be patient. Whenever my skin gets too dry I stop and use Lamelle Serra Restore Cream for a day or so.

    March 13, 2019
    Verified Review

    Helpful?

    Reply
  • Lucille Ridings

    SkinCeuticals Glycolic 10 OverNight is absolutely amazing. Since I’ve been using this amazing product I’ve noticed my fine lines demizing day by day. My skin feels fresh vibrant and renewed. Absolutely an investment.

    June 25, 2018

    Helpful?

    Reply

Leave feedback about this Cancel reply

You must be logged in to post a review.

Video

Dr Webster also recommends

pHformula

pHformula MD AGE Active Recovery

R1,030.00
Rx
pHformula
pHformula MD AGE Active Recovery
Advanced multi-corrective Anti-Ageing treatment Early or Mature ageing
R1,030.00
ADD
VIEW

NeoStrata®

NeoStrata® Lotion Plus

R840.00
Rx
NeoStrata®
NeoStrata® Lotion Plus
Extra-Strength Glycolic Lotion Face & Body
R840.00
ADD
VIEW

Dermaceutic

Dermaceutic Turn Over Cream

R1,110.00
Rx
Dermaceutic
Dermaceutic Turn Over Cream
Powerful Cell Turnover Night Cream Tolerant Skin
R1,110.00
ADD
VIEW
Shop by Top Range
  • SkinCeuticals
  • NeoStrata
  • MartiDerm
  • Huxley
  • Lamelle
  • pHformula
  • Melumé
  • ZO Skin Health
Customer Experience
  • Help Center
  • Become a Member
  • Video Consultations
  • Newsletter
  • Rx Products
  • DermaPoints Loyalty
  • Terms & Conditions
  • Clinical Studies
  • Gift Vouchers
About Us
  • Contact Us
  • Our Brands
  • Our Story
  • Podcast
  • Google Reviews
  • Distribution

Specialist online skincare store backed by a leading Dermatologist.

Facebook-f Instagram Spotify Apple

© Dermastore® 2025 All Rights Reserved

Rx

Dermastore® Rx labelled products require registration and a quick once-off multiple choice assessment.

Get Started

Learn more about Rx labelled products.

Already a member?

Login